Ubiquitin Tunes Hedgehog in Matters of the Heart

Sandii Constable, Saikat Mukhopadhyay

Research output: Contribution to journalArticlepeer-review

Abstract

Oligogenic inheritance makes the etiology of developmental diseases challenging to determine. In this issue of Developmental Cell, Kong et al., 2020 identify members of a membrane-tethered ubiquitin complex that attenuates Hedgehog signaling strength and genetically interact to regulate digit number, body patterning, and cardiac development.

Original languageEnglish (US)
Pages (from-to)385-386
Number of pages2
JournalDevelopmental cell
Volume55
Issue number4
DOIs
StatePublished - Nov 23 2020

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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