UIJ - Renal cell carcinoma with synchronous gallbladder metastasis treated with laparoscopic radical nephrectomy and cholecystectomy in the same setting

Renal cell carcinoma (RCC) with gallbladder metastasis is a very rare entity, whether as a synchronous or metachronous lesion. Additional ancillary immunohistochemical tests may be required to make the diagnosis. We report the case of a 66-year-old woman with primary RCC and a synchronous gallbladder metastasis, who underwent laparoscopic radical nephrectomy and cholecystectomy in the same setting. Gallbladder histopathology revealed clear cell RCC, similar to the primary tumor. With positive immunostaining of the tumor for CA-IX, she has responded well to interleukin-2 immunotherapy.