Ultrasound biomicroscopy and magnetic resonance imaging of reconstituted articular cartilage

K. A. Harasiewicz, H. K. Gahunia, C. Lemaire, N. B. Konyer, H. K W Kim, P. S. Babyn, K. P H Pritzker, F. S. Foster

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A system based on reconstituted articular cartilage is used to facilitate evaluation of non-invasive imaging methods such as ultrasound biomicroscopy (UBM) and magnetic resonance imaging (MRI) for assessment of osteoarthritis (OA). Chondrocytes from the superficial and deep layers of calf articular cartilage were isolated and cultured. Some cultures were treated with interleukin 1 (Il-1) and the effects on cartilage growth were studied. On days 21, 35, and 56 the cartilage cultures were examined using UBM, MRI, and histology. Cartilage thickness measured using UBM, MRI, and histology were similar with the correlation coefficients of 0.982 (P<0.0001) and 0.998 (P<0.0001) respectively. Comparisons of the UBM images with histology and MRI will be presented and potential application of the real time UBM imaging of cartilage will be discussed.

Original languageEnglish (US)
Title of host publicationProceedings of the IEEE Ultrasonics Symposium
EditorsS.C. Schneider, M. Levy, B.R. McAvoy
PublisherIEEE
Pages1149-1152
Number of pages4
Volume2
StatePublished - 1997
EventProceedings of the 1997 IEEE Ultrasonics Symposium. Part 1 (of 2) - Toronto, Can
Duration: Oct 5 1997Oct 8 1997

Other

OtherProceedings of the 1997 IEEE Ultrasonics Symposium. Part 1 (of 2)
CityToronto, Can
Period10/5/9710/8/97

ASJC Scopus subject areas

  • Engineering(all)

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    Harasiewicz, K. A., Gahunia, H. K., Lemaire, C., Konyer, N. B., Kim, H. K. W., Babyn, P. S., Pritzker, K. P. H., & Foster, F. S. (1997). Ultrasound biomicroscopy and magnetic resonance imaging of reconstituted articular cartilage. In S. C. Schneider, M. Levy, & B. R. McAvoy (Eds.), Proceedings of the IEEE Ultrasonics Symposium (Vol. 2, pp. 1149-1152). IEEE.