Abstract
A system based on reconstituted articular cartilage is used to facilitate evaluation of non-invasive imaging methods such as ultrasound biomicroscopy (UBM) and magnetic resonance imaging (MRI) for assessment of osteoarthritis (OA). Chondrocytes from the superficial and deep layers of calf articular cartilage were isolated and cultured. Some cultures were treated with interleukin 1 (Il-1) and the effects on cartilage growth were studied. On days 21, 35, and 56 the cartilage cultures were examined using UBM, MRI, and histology. Cartilage thickness measured using UBM, MRI, and histology were similar with the correlation coefficients of 0.982 (P<0.0001) and 0.998 (P<0.0001) respectively. Comparisons of the UBM images with histology and MRI will be presented and potential application of the real time UBM imaging of cartilage will be discussed.
| Original language | English (US) |
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| Title of host publication | Proceedings of the IEEE Ultrasonics Symposium |
| Editors | S.C. Schneider, M. Levy, B.R. McAvoy |
| Publisher | IEEE |
| Pages | 1149-1152 |
| Number of pages | 4 |
| Volume | 2 |
| State | Published - 1997 |
| Event | Proceedings of the 1997 IEEE Ultrasonics Symposium. Part 1 (of 2) - Toronto, Can Duration: Oct 5 1997 → Oct 8 1997 |
Other
| Other | Proceedings of the 1997 IEEE Ultrasonics Symposium. Part 1 (of 2) |
|---|---|
| City | Toronto, Can |
| Period | 10/5/97 → 10/8/97 |
ASJC Scopus subject areas
- General Engineering