@article{1d11ef950f2e48749a5dd7dd5e314d93,
title = "Understanding the association between chromosomally integrated human herpesvirus 6 and HIV disease: A cross-sectional study",
abstract = "We conducted a cross-sectional investigation to identify evidence of a potential modifying effect of chromosomally integrated human herpes virus 6 (ciHHV-6) on human immunodeficiency virus (HIV) disease progression and/or severity. ciHHV-6 was identified by detecting HHV-6 DNA in hair follicle specimens of 439 subjects. There was no statistically significant relationship between the presence of ciHHV-6 and HIV disease progression to acquired immunodeficiency syndrome. However, after adjusting for use of antiretroviral therapy, all subjects with ciHHV-6 had low severity HIV disease; these findings were not statistically significant. A multi-center study with a larger sample size will be needed to more precisely determine if there is an association between ciHHV-6 and low HIV disease severity.",
author = "Kainth, {Mundeep K.} and Fisher, {Susan G.} and Diana Fernandez and Amneris Luque and Hall, {Caroline B.} and Hoang, {Anh Thi} and Anisha Lashkari and Alexandra Peck and Lubaba Hasan and Caserta, {Mary T.}",
note = "Funding Information: Competing interests: Mary T. Caserta has received funding from the HHV-6 Foundation for unrelated projects. No other competing interests were disclosed. Funding Information: Mundeep K. Kainth received a Strong Children{\textquoteright}s Research Center Bradford Fellowship and a Developmental Center for AIDS Research pilot award. She was supported by NIH/NIAID 2 T32 AI 007464-16 during her fellowship training. Funding Information: Grant information: Mundeep K. Kainth received a Strong Children{\textquoteright}s Research Center Bradford Fellowship and a Developmental Center for AIDS Research pilot award. She was supported by NIH/NIAID 2 T32 AI 007464-16 during her fellowship training. Publisher Copyright: {\textcopyright} 2017 Kainth MK et al.",
year = "2017",
doi = "10.12688/f1000research.2-269.v2",
language = "English (US)",
volume = "2",
journal = "F1000Research",
issn = "2046-1402",
publisher = "F1000 Research Ltd.",
}