Unexpected basis for impaired Glc₃Man₉ GlcNAc₂-P-P-dolichol biosynthesis by elevated expression of GlcNAc-1-P transferase

Medicine & Life Sciences

• Dolichols 100%
• Transferases 64%
• dolichol-D-glucosylmonophosphate 47%
• Congenital Disorders of Glycosylation 16%
• CHO Cells 12%
• UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferase 9%
• lipid-linked oligosaccharides 8%
• Uridine Diphosphate 6%
• Monosaccharides 6%
• Oligosaccharides 5%
• Phenotype 3%
• Messenger RNA 3%
• Mutation 2%
• Genes 2%
• Proteins 1%

Chemical Compounds

• Disorder 53%
• Biosynthesis 52%
• Transferase Inhibitor 51%
• Glycosylation 31%
• Oligosaccharide 29%
• Mutation 26%
• Enzyme Activity 25%
• Protein 13%