Unexplained decrease in measured oxygen saturation by pulse oximetry following injection of Lymphazurin 1% (isosulfan blue) during a lymphatic mapping procedure

Robert L. Coleman, Charles W. Whitten, John O'Boyle, Bobbie Sidhu

Research output: Contribution to journalArticle

48 Scopus citations


A rare case of alteration in measured pulse oximetry during a lymphatic mapping procedure for cervical carcinoma is reported. Over a 5-min period following injection of perilesional Lymphazurin 1% dye (3 ml total), a profound pulse oximetry desaturation was observed. Concomitant arterial blood gas determinations confirmed patient's well-being. Interaction of this agent's absorptive spectroscopy and wavelengths used to measure oxygen saturation by commercial pulse oximetry devices is suspected.

Original languageEnglish (US)
Pages (from-to)126-129
Number of pages4
JournalJournal of Surgical Oncology
Issue number2
Publication statusPublished - 1999



  • Absorptive spectroscopy
  • Cervical cancer
  • Hemoglobin species
  • Sentinel node

ASJC Scopus subject areas

  • Surgery
  • Oncology

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