Unravelling the mysteries of gout by multimodality imaging

Waleed Abdellatif, Jeffrey Ding, Dina Khorshed, Kam Shojania, Savvas Nicolaou

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

Gout is a common inflammatory arthritis that manifests as an aggregate of variably symptomatic monosodium urate crystals (MSU) in the joints and surrounding tissues in addition to multisystem involvement such as genitourinary and cardiovascular systems. In recent decades, there has been a documented increase in the prevalence and incidence of gout. Risk factors for gout include obesity, dietary influences, hypertension, renal impairment, and diuretic use. A prompt diagnosis followed by uric acid lowering treatment prior to the onset of bone destruction is the goal in any suspected case of gout. Advanced imaging modalities, such as dual energy computed tomography (DECT) and ultrasonography (US), employed for the diagnosis of gout are each accompanied by advantages and disadvantages. Conventional radiography (CR), although useful in visualizing joint erosions and mineralization, is limited in its ability to diagnose gout flare. Although synovial fluid aspiration remains the gold standard for MSU crystal visualization, less-invasive imaging modalities are preferred to avoid potential complications. DECT and US in particular are useful in the diagnosis of gout. In this review, we will discuss the current state and role of imaging in the detection of gout.

Original languageEnglish (US)
Pages (from-to)S17-S23
JournalSeminars in Arthritis and Rheumatism
Volume50
Issue number3
DOIs
StatePublished - Jun 2020
Externally publishedYes

Keywords

  • Dual energy computed tomography
  • emergency radiology
  • Gout
  • gouty arthritis
  • MSU crystals
  • review
  • ultrasonography

ASJC Scopus subject areas

  • Rheumatology
  • Anesthesiology and Pain Medicine

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