Unusuaj type of mitochondria] DNA in mice lacking a maternally transmitted antigen

Stephen D. Fems; Uzi Ritte; Kirsten Fischer Lindahl; Ellen M. Prager; Allan C. Wilson

doi:10.1093/nar/11.9.2917

Unusuaj type of mitochondria] DNA in mice lacking a maternally transmitted antigen

Stephen D. Fems, Uzi Ritte, Kirsten Fischer Lindahl, Ellen M. Prager, Allan C. Wilson

Immunology

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Mice that lack a maternally transmitted antigen (Mta) on the cell surface share a distinctive type of mitochondrial DNA. This 1s evident from restriction analyses of mitochondrial DMAs from 25 strains of mice whose antigenic state 1s known. One hundred sixty-eight cleavage sites have been mapped 1n the mitochondrial DNA of Mta mice. Detailed maps for the 8 other types of mitochondrial DNA detected 1n the survey have also been prepared. The Mta mice are estimated to differ from those expressing the antigen by 108 to 141 base substitutions at widely scattered points 1n the mitochondrial genome.

Original language	English (US)
Pages (from-to)	2917-2926
Number of pages	10
Journal	Nucleic acids research
Volume	11
Issue number	9
DOIs	https://doi.org/10.1093/nar/11.9.2917
State	Published - May 11 1983

ASJC Scopus subject areas

Genetics

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title = "Unusuaj type of mitochondria] DNA in mice lacking a maternally transmitted antigen",

abstract = "Mice that lack a maternally transmitted antigen (Mta) on the cell surface share a distinctive type of mitochondrial DNA. This 1s evident from restriction analyses of mitochondrial DMAs from 25 strains of mice whose antigenic state 1s known. One hundred sixty-eight cleavage sites have been mapped 1n the mitochondrial DNA of Mta mice. Detailed maps for the 8 other types of mitochondrial DNA detected 1n the survey have also been prepared. The Mta mice are estimated to differ from those expressing the antigen by 108 to 141 base substitutions at widely scattered points 1n the mitochondrial genome.",

author = "Fems, {Stephen D.} and Uzi Ritte and Lindahl, {Kirsten Fischer} and Prager, {Ellen M.} and Wilson, {Allan C.}",

note = "Funding Information: ACKNOWLEDGEMENTS We thank those who supplied mice and B. S. Chapman, D. A. Clayton, andC. Janeway for discussion. The Basel Institute for Immunology was founded and1s supported by F. Hoffmann-La Roche andCo.,Ltd.,Basel, Switzerland. This research was supported by grants from the U.S. National Science Foundation and the National Institutes of Health.",

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doi = "10.1093/nar/11.9.2917",

language = "English (US)",

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T1 - Unusuaj type of mitochondria] DNA in mice lacking a maternally transmitted antigen

AU - Fems, Stephen D.

AU - Ritte, Uzi

AU - Lindahl, Kirsten Fischer

AU - Prager, Ellen M.

AU - Wilson, Allan C.

N1 - Funding Information: ACKNOWLEDGEMENTS We thank those who supplied mice and B. S. Chapman, D. A. Clayton, andC. Janeway for discussion. The Basel Institute for Immunology was founded and1s supported by F. Hoffmann-La Roche andCo.,Ltd.,Basel, Switzerland. This research was supported by grants from the U.S. National Science Foundation and the National Institutes of Health.

PY - 1983/5/11

Y1 - 1983/5/11

N2 - Mice that lack a maternally transmitted antigen (Mta) on the cell surface share a distinctive type of mitochondrial DNA. This 1s evident from restriction analyses of mitochondrial DMAs from 25 strains of mice whose antigenic state 1s known. One hundred sixty-eight cleavage sites have been mapped 1n the mitochondrial DNA of Mta mice. Detailed maps for the 8 other types of mitochondrial DNA detected 1n the survey have also been prepared. The Mta mice are estimated to differ from those expressing the antigen by 108 to 141 base substitutions at widely scattered points 1n the mitochondrial genome.

AB - Mice that lack a maternally transmitted antigen (Mta) on the cell surface share a distinctive type of mitochondrial DNA. This 1s evident from restriction analyses of mitochondrial DMAs from 25 strains of mice whose antigenic state 1s known. One hundred sixty-eight cleavage sites have been mapped 1n the mitochondrial DNA of Mta mice. Detailed maps for the 8 other types of mitochondrial DNA detected 1n the survey have also been prepared. The Mta mice are estimated to differ from those expressing the antigen by 108 to 141 base substitutions at widely scattered points 1n the mitochondrial genome.

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Unusuaj type of mitochondria] DNA in mice lacking a maternally transmitted antigen

Abstract

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