Unusual malignant epithelial tumors of the gallbladder

J. Albores-Saavedra, K. Molberg, D. E. Henson

51 Scopus citations


Most malignant epithelial tumors of the gallbladder are heterogenous and classified as adenocarcinomas. The authors report a previously unrecognized group of unusual gallbladder carcinomas including two cases of signet ring cell carcinoma in situ, three of cribriform invasive adenocarcinoma, and one of adenocarcinoma with pseudoangiosarcomatous features. In addition, the authors review their material and update the information on clear cell, small cell, and undifferentiated carcinoma of the gallbladder. A new morphologic variant of undifferentiated carcinoma mimicking lobular carcinoma of the breast is identified. The clinical, morphologic, and immunohistochemical features of these unusual neoplasms are emphasized.

Original languageEnglish (US)
Pages (from-to)326-338
Number of pages13
JournalSeminars in Diagnostic Pathology
Issue number4
Publication statusPublished - 1996



  • adenocarcinoma with pseudoangiosarcomatous features
  • clear cell carcinoma
  • cribriform adenocarcinoma
  • gallbladder
  • Signet ring cell carcinoma in situ
  • small cell carcinoma
  • undifferentiated carcinoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

Albores-Saavedra, J., Molberg, K., & Henson, D. E. (1996). Unusual malignant epithelial tumors of the gallbladder. Seminars in Diagnostic Pathology, 13(4), 326-338.