Abstract
Specific extraction of Z bands, intercalated disks and desmosomes was accomplished with molar concentrations of urea. Thick and thin filaments and M line material were undisturbed, demonstrating that the Z band protein is not similar to actin, myosin, or the M-line protein. The literature indicates that the tropomyosins are the only other structural proteins present in sufficient amounts to account for the extracted Z bands. However, the evidence for a lipid-protein association in the Z bands is considered and is further supported by the close association of the dense material of the Z bands, intercalated disks, and desmosomes with the lipoprotein cell membranes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 181-189 |
| Number of pages | 9 |
| Journal | Journal of Ultrasructure Research |
| Volume | 24 |
| Issue number | 3-4 |
| DOIs | |
| State | Published - Aug 1968 |
ASJC Scopus subject areas
- Anatomy
- Molecular Biology
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Rash, J. E., Shay, J. W., & Biesele, J. J. (1968). Urea extraction of Z bands, intercalated disks, and desmosomes. Journal of Ultrasructure Research, 24(3-4), 181-189. https://doi.org/10.1016/S0022-5320(68)90057-9