Urinary incontinence and pelvic organ prolapse in women with Marfan or Ehlers-Danlos syndrome

Michael E. Carley, Joseph Schaffer

Research output: Contribution to journalArticlepeer-review

127 Scopus citations

Abstract

OBJECTIVE: This study was undertaken to determine the prevalence of urinary incontinence and pelvic organ prolapse in a cohort of women with either Marfan syndrome or Ehlers-Danlos syndrome. STUDY DESIGN: Female patients with either Marfan syndrome or Ehlers-Danlos syndrome were identified through a medical records search at two urban hospitals. Each patient's medical record was reviewed, and the history of pelvic organ prolapse and urinary incontinence was obtained through telephone interview. RESULTS: Twelve women with Marfan syndrome were identified. Among these women 5 (42%) reported a history of urinary incontinence and 4 (33%) reported a history of pelvic organ prolapse. Eight women with Ehlers-Danlos syndrome were identified. Among these women 4 (50%) reported a history of urinary incontinence and 6 (75%) reported a history of pelvic organ prolapse. CONCLUSIONS: Women with Marfan or Ehlers-Danlos syndrome have high rates of urinary incontinence and pelvic organ prolapse. This finding supports the hypothesized etiologic role of connective tissue disorders as a factor in the pathogenesis of these conditions.

Original languageEnglish (US)
Pages (from-to)1021-1023
Number of pages3
JournalAmerican journal of obstetrics and gynecology
Volume182
Issue number5
DOIs
StatePublished - Jan 1 2000

Keywords

  • Ehlers-Danlos syndrome
  • Incontinence
  • Marfan syndrome
  • Prolapse

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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