Urinary incontinence and pelvic organ prolapse in women with Marfan or Ehlers-Danlos syndrome

Michael E. Carley, Joseph Schaffer

Research output: Contribution to journalArticle

125 Citations (Scopus)

Abstract

OBJECTIVE: This study was undertaken to determine the prevalence of urinary incontinence and pelvic organ prolapse in a cohort of women with either Marfan syndrome or Ehlers-Danlos syndrome. STUDY DESIGN: Female patients with either Marfan syndrome or Ehlers-Danlos syndrome were identified through a medical records search at two urban hospitals. Each patient's medical record was reviewed, and the history of pelvic organ prolapse and urinary incontinence was obtained through telephone interview. RESULTS: Twelve women with Marfan syndrome were identified. Among these women 5 (42%) reported a history of urinary incontinence and 4 (33%) reported a history of pelvic organ prolapse. Eight women with Ehlers-Danlos syndrome were identified. Among these women 4 (50%) reported a history of urinary incontinence and 6 (75%) reported a history of pelvic organ prolapse. CONCLUSIONS: Women with Marfan or Ehlers-Danlos syndrome have high rates of urinary incontinence and pelvic organ prolapse. This finding supports the hypothesized etiologic role of connective tissue disorders as a factor in the pathogenesis of these conditions.

Original languageEnglish (US)
Pages (from-to)1021-1023
Number of pages3
JournalAmerican Journal of Obstetrics and Gynecology
Volume182
Issue number5
DOIs
StatePublished - 2000

Fingerprint

Ehlers-Danlos Syndrome
Pelvic Organ Prolapse
Urinary Incontinence
Marfan Syndrome
Medical Records
Urban Hospitals
Connective Tissue
History
Interviews

Keywords

  • Ehlers-Danlos syndrome
  • Incontinence
  • Marfan syndrome
  • Prolapse

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Urinary incontinence and pelvic organ prolapse in women with Marfan or Ehlers-Danlos syndrome. / Carley, Michael E.; Schaffer, Joseph.

In: American Journal of Obstetrics and Gynecology, Vol. 182, No. 5, 2000, p. 1021-1023.

Research output: Contribution to journalArticle

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