Urine collection method for the diagnosis of congenital cytomegalovirus infection

Shannon A. Ross, Amina Ahmed, April L. Palmer, Marian G. Michaels, Pablo J. Sánchez, Audra Stewart, David I. Bernstein, Kristina Feja, Zdenek Novak, Karen B. Fowler, Suresh B. Boppana

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Congenital cytomegalovirus infection is traditionally diagnosed by virus detection in saliva or urine. Virus culture was positive in significantly fewer urine samples collected using cotton balls in diapers (55.2%) than with samples collected by bags (93.2%) from newborns screened positive for CMV in saliva. However, polymerase chain reaction was positive in 95% of urine samples regardless of the collection method.

Original languageEnglish (US)
Pages (from-to)903-905
Number of pages3
JournalPediatric Infectious Disease Journal
Volume34
Issue number8
DOIs
StatePublished - Aug 21 2015

Keywords

  • collection
  • cotton
  • cytomegalovirus
  • urine

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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  • Cite this

    Ross, S. A., Ahmed, A., Palmer, A. L., Michaels, M. G., Sánchez, P. J., Stewart, A., Bernstein, D. I., Feja, K., Novak, Z., Fowler, K. B., & Boppana, S. B. (2015). Urine collection method for the diagnosis of congenital cytomegalovirus infection. Pediatric Infectious Disease Journal, 34(8), 903-905. https://doi.org/10.1097/INF.0000000000000757