Urine vapor pattern for olivopontocerebellar degeneration

Roger N. Rosenberg, Arthur B. Robinson, David Partridge

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Autosomal dominant olivopontocerebellar degeneration was evaluated in a family numbering 414 living members. Urine samples were obtained from 5 affected and 5 unaffected not at-risk family members after 4 days on a synthetic diet. 159 urine vapor constituents were measured by gas-liquid and ion-exchange chromatography and a non-correlation index was calculated. 2 distinct populations of urine vapor patterns were identified which conformed to the normal and disease affected groups, thus a diagnostically useful pattern for this disease in this family has been demonstrated which will be helpful in genetic counselling and potential elimination of the disease.

Original languageEnglish (US)
Pages (from-to)365-368
Number of pages4
JournalClinical Biochemistry
Volume8
Issue number1-6
DOIs
StatePublished - 1975

Fingerprint

Olivopontocerebellar Atrophies
Vapors
Urine
Disease Eradication
Formulated Food
Genetic Counseling
Ion Exchange Chromatography
Nutrition
Chromatography
Ion exchange
Gases
Liquids
Population

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Urine vapor pattern for olivopontocerebellar degeneration. / Rosenberg, Roger N.; Robinson, Arthur B.; Partridge, David.

In: Clinical Biochemistry, Vol. 8, No. 1-6, 1975, p. 365-368.

Research output: Contribution to journalArticle

Rosenberg, Roger N. ; Robinson, Arthur B. ; Partridge, David. / Urine vapor pattern for olivopontocerebellar degeneration. In: Clinical Biochemistry. 1975 ; Vol. 8, No. 1-6. pp. 365-368.
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