Anomalies of the urinary tract rank third to fourth among congenital malformations and occur in about 10 per cent of the population. These anomalies generally are the result of interaction between environmental factors, such as maternal illness and exposure to noxious substances, and genetic factors, including monogenic mutations, chromosomal anomalies or multigenic interactions. It is estimated that approximately 15 per cent of all urogenital anomalies are owing to chromosomal aberrations, 31 per cent are multifactorial and 9 per cent are secondary to defined teratogenic factors during gestation. Frequently, urogenital anomalies are part of multiple congenital malformations involving other organ systems. The aim of this review is to list as completely as possible genetic disorders associated with different genitourinary anomalies.
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