Use of botulinum toxin type A in pediatric patients with cerebral palsy

A three-center retrospective chart review

M. E. Gormley, D. Gaebler-Spira, M. R. Delgado

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Over the last several years, botulinum toxin type A has gained widespread use for the management of focal spasticity in children with cerebral palsy. To assess the current patterns of botulinum toxin type A use in the clinical setting, the dose, muscles injected, age at injection, and interval between injections of botulinum toxin type A treatments were examined in a retrospective chart review of children with cerebral palsy (N = 270) over a 2-year period at three major treatment centers. The average dose of botulinum toxin type A across the three centers ranged from 7.7 to 10.8 U/kg body weight, and the average total amount of botulinum toxin type A injected at a single visit ranged from 154 to 205 U. The majority of botulinum toxin type A injections were to the muscles to the lower limbs. The average age at first injection was 6.2 years, and the average interval between injections ranged from 134 to 199 days.

Original languageEnglish (US)
Pages (from-to)113-118
Number of pages6
JournalJournal of Child Neurology
Volume16
Issue number2
StatePublished - 2001

Fingerprint

Type A Botulinum Toxins
Cerebral Palsy
Pediatrics
Injections
Muscles
Lower Extremity
Body Weight
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health

Cite this

Use of botulinum toxin type A in pediatric patients with cerebral palsy : A three-center retrospective chart review. / Gormley, M. E.; Gaebler-Spira, D.; Delgado, M. R.

In: Journal of Child Neurology, Vol. 16, No. 2, 2001, p. 113-118.

Research output: Contribution to journalArticle

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