Use of diffusion and perfusion magnetic resonance imaging as a tool in acute stroke clinical trials

Steven Warach

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

In light of the slow progress in developing effective therapies for ischemic stroke, magnetic resonance imaging techniques have emerged as new tools in stroke clinical trials. Rapid imaging with magnetic resonance imaging, diffusion weighted imaging, perfusion imaging and angiography are being incorporated into phase II and phase III stroke trials to optimize patient selection based on positive imaging diagnosis of the ischemic pathophysiology specifically related to a drug's mechanism of action and as a direct biomarker of the effect of a treatment's effect on the brain.

Original languageEnglish (US)
Article number038
Pages (from-to)38-44
Number of pages7
JournalCurrent Controlled Trials in Cardiovascular Medicine
Volume2
Issue number1
DOIs
StatePublished - 2001

Fingerprint

Diffusion Magnetic Resonance Imaging
Magnetic Resonance Angiography
Stroke
Clinical Trials
Perfusion Imaging
Patient Selection
Angiography
Biomarkers
Magnetic Resonance Imaging
Brain
Pharmaceutical Preparations
Therapeutics

Keywords

  • Clinical trials
  • Diffusion
  • Magnetic resonance imaging
  • Perfusion
  • Stroke

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Use of diffusion and perfusion magnetic resonance imaging as a tool in acute stroke clinical trials. / Warach, Steven.

In: Current Controlled Trials in Cardiovascular Medicine, Vol. 2, No. 1, 038, 2001, p. 38-44.

Research output: Contribution to journalArticle

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