Use of diffusion tensor imaging in glioma resection

Kalil G. Abdullah, Daniel Lubelski, Paolo G.P. Nucifora, Steven Brem

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

Diffusion tensor imaging (DTI) is increasingly used in the resection of both high- and low-grade gliomas. Whereas conventional MRI techniques provide only anatomical information, DTI offers data on CNS connectivity by enabling visualization of important white matter tracts in the brain. Importantly, DTI allows neurosurgeons to better guide their surgical approach and resection. Here, the authors review basic scientific principles of DTI, include a primer on the technology and image acquisition, and outline the modality's evolution as a frequently used tool for glioma resection. Current literature supporting its use is summarized, highlighting important clinical studies on the application of DTI in preoperative planning for glioma resection, preoperative diagnosis, and postoperative outcomes. The authors conclude with a review of future directions for this technology.

Original languageEnglish (US)
Article numberE1
JournalNeurosurgical focus
Volume34
Issue number4
DOIs
StatePublished - Apr 1 2013

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Keywords

  • Brain mapping
  • Connectome
  • Diffusion tensor imaging
  • Glioma

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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