Use of DNA probes from the 5′ flanking region of the HLA-B gene to examine polymorphism at the HLA-B locus

Karyn Steere, Beth Sidwell, Robin Leach, Francis E. Ward, Joel D. Taurog, Harry T. Orr

Research output: Contribution to journalArticle

9 Scopus citations


Two DNA probes isolated from the region 5′ to the HLA-B gene are described. One of these, pCH6, detects a TaqI polymorphism which is correlated with serological alleles of HLA-B. Both probes are used to show a high level of DNA sequence homology between the 5′ flanking region of HLA-B and HLA-C.

Original languageEnglish (US)
Pages (from-to)137-147
Number of pages11
JournalHuman Immunology
Issue number2
StatePublished - Jun 1986


ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this