TY - JOUR
T1 - Use of 18F-fludeoxyglucose-positron emission tomography/computed tomography for patient management and outcome in oropharyngeal squamous cell carcinoma a review
AU - Taghipour, Mehdi
AU - Sheikhbahaei, Sara
AU - Marashdeh, Wael
AU - Solnes, Lilja
AU - Kiess, Anna
AU - Subramaniam, Rathan M.
N1 - Publisher Copyright:
Copyright 2016 American Medical Association. All rights reserved.
PY - 2016/1
Y1 - 2016/1
N2 - 18F-fludeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) has been performed widely in diagnosis and management of patients with oropharyngeal squamous cell carcinoma (OPSCC). This review summarizes the literature on this tool in the management of these patients. The use of FDG-PET/CT helps in accurate staging of primary tumor, nodal involvement, and distant metastasis of patients with OPSCC. Contrast-enhanced FDG-PET/CT combines high-resolution CT and functional FDG-PET, providing the optimum imaging information for patient management. Using contrast-enhanced PET/CT leads to a combined anatomic and metabolic approach to radiation therapy planning in OPSCC. Moreover, PET/CT not only is a good modality for therapy assessment but also is a powerful tool in early recurrence detection of OPSCC. Finally, the PET/CT parameters provide survival information in patients with OPSCC; however, further studies are needed to introduce a scoring system to use clinically for prognosis prediction.
AB - 18F-fludeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) has been performed widely in diagnosis and management of patients with oropharyngeal squamous cell carcinoma (OPSCC). This review summarizes the literature on this tool in the management of these patients. The use of FDG-PET/CT helps in accurate staging of primary tumor, nodal involvement, and distant metastasis of patients with OPSCC. Contrast-enhanced FDG-PET/CT combines high-resolution CT and functional FDG-PET, providing the optimum imaging information for patient management. Using contrast-enhanced PET/CT leads to a combined anatomic and metabolic approach to radiation therapy planning in OPSCC. Moreover, PET/CT not only is a good modality for therapy assessment but also is a powerful tool in early recurrence detection of OPSCC. Finally, the PET/CT parameters provide survival information in patients with OPSCC; however, further studies are needed to introduce a scoring system to use clinically for prognosis prediction.
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U2 - 10.1001/jamaoto.2015.2607
DO - 10.1001/jamaoto.2015.2607
M3 - Review article
C2 - 26583955
AN - SCOPUS:84955443615
SN - 2168-6181
VL - 142
SP - 79
EP - 85
JO - JAMA Otolaryngology - Head and Neck Surgery
JF - JAMA Otolaryngology - Head and Neck Surgery
IS - 1
ER -