Usefulness of an algebraic fitting of nomograms allowing evaluation detrusor contractility in women

F. A. Valentini, B. G. Marti, P. P. Nelson, P. E. Zimmern, G. Robain

Research output: Contribution to journalArticle

Abstract

Aims: Nomograms based on Valentini-Besson-Nelson (VBN) model implying only 3 measurements (filling bladder volume, maximum flow-rate [Qmax] and detrusor pressure at Qmax) were recently developed to evaluate detrusor contractility (k) and urethral obstruction (U) in women. As their algebraic fitting leads to fast evaluations (Excel® software), our aims were applications to populations of non-neurologic women without and with bladder outlet obstruction (BOO). Methods: The software was applied to measurements obtained during pressure flow studies. Hidden hypothesis of nomograms were no significant contribution of abdominal pressure between onset of flow and Qmax and standard nervous excitations until Qmax. Studied populations were 202 women without symptom suggestive of obstruction and 125 women with proven anatomical urethral obstruction who underwent urodynamic study. Results: For non-obstructed women, a good agreement was found between the values of . k and . U obtained using nomograms or a complete VBN analysis of the recorded curves. Whatever the obstructive status, there was a good correlation between the value of . k and . U. Evolution with ageing was similar with higher values of . k and . U in the BOO group. Curves . k(age) and . U(age) gave coefficients allowing an age adjustment. The high . k value in the detrusor overactive (DO) group was consistent with a similar effect to that of BOO on the detrusor. Conclusion: Evaluation of detrusor contractility (k) and urethral obstruction (U) can be obtained from the point of Qmax during pressure-flow study. Evolution with ageing is similar with (higher values) or without BOO. DO also induces an increased detrusor contractility. Level of evidence: 4.

Original languageEnglish (US)
JournalProgres en Urologie
DOIs
StateAccepted/In press - Apr 29 2016

Fingerprint

Nomograms
Urinary Bladder Neck Obstruction
Urethral Obstruction
Pressure
Overactive Urinary Bladder
Software
Urodynamics
Population
Urinary Bladder

Keywords

  • Bladder outlet obstruction
  • Detrusor contractility
  • Nomograms
  • Women

ASJC Scopus subject areas

  • Urology

Cite this

Usefulness of an algebraic fitting of nomograms allowing evaluation detrusor contractility in women. / Valentini, F. A.; Marti, B. G.; Nelson, P. P.; Zimmern, P. E.; Robain, G.

In: Progres en Urologie, 29.04.2016.

Research output: Contribution to journalArticle

@article{18a242e66e25435385a7d83d5e71dc71,
title = "Usefulness of an algebraic fitting of nomograms allowing evaluation detrusor contractility in women",
abstract = "Aims: Nomograms based on Valentini-Besson-Nelson (VBN) model implying only 3 measurements (filling bladder volume, maximum flow-rate [Qmax] and detrusor pressure at Qmax) were recently developed to evaluate detrusor contractility (k) and urethral obstruction (U) in women. As their algebraic fitting leads to fast evaluations (Excel{\circledR} software), our aims were applications to populations of non-neurologic women without and with bladder outlet obstruction (BOO). Methods: The software was applied to measurements obtained during pressure flow studies. Hidden hypothesis of nomograms were no significant contribution of abdominal pressure between onset of flow and Qmax and standard nervous excitations until Qmax. Studied populations were 202 women without symptom suggestive of obstruction and 125 women with proven anatomical urethral obstruction who underwent urodynamic study. Results: For non-obstructed women, a good agreement was found between the values of . k and . U obtained using nomograms or a complete VBN analysis of the recorded curves. Whatever the obstructive status, there was a good correlation between the value of . k and . U. Evolution with ageing was similar with higher values of . k and . U in the BOO group. Curves . k(age) and . U(age) gave coefficients allowing an age adjustment. The high . k value in the detrusor overactive (DO) group was consistent with a similar effect to that of BOO on the detrusor. Conclusion: Evaluation of detrusor contractility (k) and urethral obstruction (U) can be obtained from the point of Qmax during pressure-flow study. Evolution with ageing is similar with (higher values) or without BOO. DO also induces an increased detrusor contractility. Level of evidence: 4.",
keywords = "Bladder outlet obstruction, Detrusor contractility, Nomograms, Women",
author = "Valentini, {F. A.} and Marti, {B. G.} and Nelson, {P. P.} and Zimmern, {P. E.} and G. Robain",
year = "2016",
month = "4",
day = "29",
doi = "10.1016/j.purol.2016.06.010",
language = "English (US)",
journal = "Progres en Urologie",
issn = "1166-7087",
publisher = "Elsevier Masson",

}

TY - JOUR

T1 - Usefulness of an algebraic fitting of nomograms allowing evaluation detrusor contractility in women

AU - Valentini, F. A.

AU - Marti, B. G.

AU - Nelson, P. P.

AU - Zimmern, P. E.

AU - Robain, G.

PY - 2016/4/29

Y1 - 2016/4/29

N2 - Aims: Nomograms based on Valentini-Besson-Nelson (VBN) model implying only 3 measurements (filling bladder volume, maximum flow-rate [Qmax] and detrusor pressure at Qmax) were recently developed to evaluate detrusor contractility (k) and urethral obstruction (U) in women. As their algebraic fitting leads to fast evaluations (Excel® software), our aims were applications to populations of non-neurologic women without and with bladder outlet obstruction (BOO). Methods: The software was applied to measurements obtained during pressure flow studies. Hidden hypothesis of nomograms were no significant contribution of abdominal pressure between onset of flow and Qmax and standard nervous excitations until Qmax. Studied populations were 202 women without symptom suggestive of obstruction and 125 women with proven anatomical urethral obstruction who underwent urodynamic study. Results: For non-obstructed women, a good agreement was found between the values of . k and . U obtained using nomograms or a complete VBN analysis of the recorded curves. Whatever the obstructive status, there was a good correlation between the value of . k and . U. Evolution with ageing was similar with higher values of . k and . U in the BOO group. Curves . k(age) and . U(age) gave coefficients allowing an age adjustment. The high . k value in the detrusor overactive (DO) group was consistent with a similar effect to that of BOO on the detrusor. Conclusion: Evaluation of detrusor contractility (k) and urethral obstruction (U) can be obtained from the point of Qmax during pressure-flow study. Evolution with ageing is similar with (higher values) or without BOO. DO also induces an increased detrusor contractility. Level of evidence: 4.

AB - Aims: Nomograms based on Valentini-Besson-Nelson (VBN) model implying only 3 measurements (filling bladder volume, maximum flow-rate [Qmax] and detrusor pressure at Qmax) were recently developed to evaluate detrusor contractility (k) and urethral obstruction (U) in women. As their algebraic fitting leads to fast evaluations (Excel® software), our aims were applications to populations of non-neurologic women without and with bladder outlet obstruction (BOO). Methods: The software was applied to measurements obtained during pressure flow studies. Hidden hypothesis of nomograms were no significant contribution of abdominal pressure between onset of flow and Qmax and standard nervous excitations until Qmax. Studied populations were 202 women without symptom suggestive of obstruction and 125 women with proven anatomical urethral obstruction who underwent urodynamic study. Results: For non-obstructed women, a good agreement was found between the values of . k and . U obtained using nomograms or a complete VBN analysis of the recorded curves. Whatever the obstructive status, there was a good correlation between the value of . k and . U. Evolution with ageing was similar with higher values of . k and . U in the BOO group. Curves . k(age) and . U(age) gave coefficients allowing an age adjustment. The high . k value in the detrusor overactive (DO) group was consistent with a similar effect to that of BOO on the detrusor. Conclusion: Evaluation of detrusor contractility (k) and urethral obstruction (U) can be obtained from the point of Qmax during pressure-flow study. Evolution with ageing is similar with (higher values) or without BOO. DO also induces an increased detrusor contractility. Level of evidence: 4.

KW - Bladder outlet obstruction

KW - Detrusor contractility

KW - Nomograms

KW - Women

UR - http://www.scopus.com/inward/record.url?scp=84978886740&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84978886740&partnerID=8YFLogxK

U2 - 10.1016/j.purol.2016.06.010

DO - 10.1016/j.purol.2016.06.010

M3 - Article

JO - Progres en Urologie

JF - Progres en Urologie

SN - 1166-7087

ER -