TY - JOUR
T1 - Using psychosis biotypes and the Framingham model for parsing psychosis biology
AU - Tamminga, Carol A.
AU - Pearlson, Godfrey
AU - Gershon, Elliot
AU - Keedy, Sarah
AU - Hudgens-Haney, Matthew E.
AU - Ivleva, Elena I.
AU - Parker, David A.
AU - McDowell, Jennifer E.
AU - Clementz, Brett
N1 - Funding Information:
Funding was provided by NIH and NIMH - Bipolar and Schizophrenia Network for Intermediate Phenotypes 2 (BSNIP2) is comprised of the following five supporting grants: MH077851 ; MH077945 ; MH078113 ; MH103366 ; MH103368.
Publisher Copyright:
© 2022
PY - 2022/4
Y1 - 2022/4
N2 - The Bipolar-Schizophrenia Network for Intermediate Phenotypes (B-SNIP) has invested in the collection and use of multiple biomarkers in individuals with psychosis. We expect psychosis biology and its distinctive types to be reflected in the biomarkers, as they are the ‘behaviors’ of the brain. Like infectious diseases, we expect the etiologies of these biomarker-driven entities to be multiple and complex. Biomarkers have not yet been annotated with disease characteristics and need to be. As a model, we seek to adopt aspects of the Framingham Heart Study (FHS) to guide and organize these observations.
AB - The Bipolar-Schizophrenia Network for Intermediate Phenotypes (B-SNIP) has invested in the collection and use of multiple biomarkers in individuals with psychosis. We expect psychosis biology and its distinctive types to be reflected in the biomarkers, as they are the ‘behaviors’ of the brain. Like infectious diseases, we expect the etiologies of these biomarker-driven entities to be multiple and complex. Biomarkers have not yet been annotated with disease characteristics and need to be. As a model, we seek to adopt aspects of the Framingham Heart Study (FHS) to guide and organize these observations.
UR - http://www.scopus.com/inward/record.url?scp=85124204101&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85124204101&partnerID=8YFLogxK
U2 - 10.1016/j.schres.2022.01.018
DO - 10.1016/j.schres.2022.01.018
M3 - Article
C2 - 35123865
AN - SCOPUS:85124204101
SN - 0920-9964
VL - 242
SP - 132
EP - 134
JO - Schizophrenia Research
JF - Schizophrenia Research
ER -