Validation and implementation of the fifth-generation high sensitivity Troponin T (hs-TnT) assay at a large teaching county hospital. A laboratory-driven multi-speciality effort

Ibrahim A Hashim, Rebecca Vigen, Fernabelle Fernandez, Amy Yu, Bryan Bertulfo, Lorie Thibodeaux, Sandeep R Das, Deborah Diercks, James A de Lemos, Patricia Kutscher

Research output: Contribution to journalLetter

1 Scopus citations


We describe the validation and implementation of the new 5th generation high sensitivity Troponin T assay (Roche Diagnostics®). In addition to the assay improved sensitivity, the numerical values, reporting units, reference intervals, and critical limits are markedly different. We describe the use of clinical correlation as the basis for implementation and validation of the fifth-generation hs-TnT assay at a large teaching county hospital.

Original languageEnglish (US)
Pages (from-to)85-87
Number of pages3
JournalClinica Chimica Acta
StatePublished - Aug 1 2019



  • 5th generation hs-TnT
  • High sensitivity Troponin T
  • Implementation

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical

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