Validation of a physician global assessment tool for vitiligo extent: Results of an international vitiligo expert meeting

the participants of the Rome International VGICC /VIS Workshop

doi:10.1111/pcmr.12784

Validation of a physician global assessment tool for vitiligo extent: Results of an international vitiligo expert meeting

the participants of the Rome International VGICC /VIS Workshop

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Currently, vitiligo lacks a validated Physician Global Assessment (PGA) for disease extent. This PGA can be used to stratify and interpret the numeric scores obtained by the Vitiligo Extent Score (VES). We investigated the interrater reliability of a 5-point PGA scale during an international vitiligo workshop. Vitiligo experts from five different continents rated photographs of non-segmental vitiligo patients with varying degrees of extent with the PGA score. Good interrater agreements (intraclass correlation coefficient >0.6) were observed between the raters overall and within each continent. All hypotheses to evaluate construct validity were confirmed. Median VES values per category were for limited 1.10 [IQR: 0.21–1.67], moderate 3.17 [IQR: 1.75–6.21], extensive 9.58 [IQR: 6.21–13.03] and very extensive 42.67 [IQR: 21.20–42.67]. Defined categories for vitiligo extent can be valuable for inclusion criteria and may impact future reimbursement criteria.

Original language	English (US)
Pages (from-to)	728-733
Number of pages	6
Journal	Pigment Cell and Melanoma Research
Volume	32
Issue number	5
DOIs	https://doi.org/10.1111/pcmr.12784
State	Published - 2019

Keywords

body surface area
extent
global assessment
outcome measure
severity
vitiligo

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
Dermatology
Oncology

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10.1111/pcmr.12784

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@article{da1a538914d14494ab3b5451a919200f,

title = "Validation of a physician global assessment tool for vitiligo extent: Results of an international vitiligo expert meeting",

abstract = "Currently, vitiligo lacks a validated Physician Global Assessment (PGA) for disease extent. This PGA can be used to stratify and interpret the numeric scores obtained by the Vitiligo Extent Score (VES). We investigated the interrater reliability of a 5-point PGA scale during an international vitiligo workshop. Vitiligo experts from five different continents rated photographs of non-segmental vitiligo patients with varying degrees of extent with the PGA score. Good interrater agreements (intraclass correlation coefficient >0.6) were observed between the raters overall and within each continent. All hypotheses to evaluate construct validity were confirmed. Median VES values per category were for limited 1.10 [IQR: 0.21–1.67], moderate 3.17 [IQR: 1.75–6.21], extensive 9.58 [IQR: 6.21–13.03] and very extensive 42.67 [IQR: 21.20–42.67]. Defined categories for vitiligo extent can be valuable for inclusion criteria and may impact future reimbursement criteria.",

keywords = "body surface area, extent, global assessment, outcome measure, severity, vitiligo",

author = "{the participants of the Rome International VGICC /VIS Workshop} and {van Geel}, Nanja and Albert Wolkerstorfer and Khaled Ezzedine and Pandya, {Amit G.} and Marcel Bekkenk and Lynda Grine and {Van Belle}, Sarah and Lommerts, {Janny E.} and Iltefat Hamzavi and Harris, {John E.} and Viktoria Eleftheriadou and Samia Esmat and Kang, {Hee Young} and Prasad Kumarasinghe and Lan, {Cheng Che E.} and Davinder Parsad and Noufal Raboobee and {Flora Xiang}, Leihong and Tamio Suzuki and Prinsen, {Cecilia A.} and Alain Taieb and Mauro Picardo and Reinhart Speeckaert and Tag Anbar and Mohamed Anbar and La{\"i}la Benzekri and Markus B{\"o}hm and Ca{\"i}o Castro and Tania Cestari and Yvon Gauthier and Maria Gnarra and Jorge Hinojosa and Jung, {Min Bae} and Ichiro Katayama and Kim, {Ki Ho} and {Eric Lan}, {Cheng Che} and Lee, {Seung Chung} and {Le Poole}, Caroline and Henry Lim and Silvia Moretti and Julien Seneschal and Richard Spritz and {van Geel}, Nanja and Flora Xiang",

note = "Publisher Copyright: {\textcopyright} 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd",

year = "2019",

doi = "10.1111/pcmr.12784",

language = "English (US)",

volume = "32",

pages = "728--733",

journal = "Pigment Cell and Melanoma Research",

issn = "1755-1471",

publisher = "Wiley-Blackwell",

number = "5",

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TY - JOUR

T1 - Validation of a physician global assessment tool for vitiligo extent

T2 - Results of an international vitiligo expert meeting

AU - the participants of the Rome International VGICC /VIS Workshop

AU - van Geel, Nanja

AU - Wolkerstorfer, Albert

AU - Ezzedine, Khaled

AU - Pandya, Amit G.

AU - Bekkenk, Marcel

AU - Grine, Lynda

AU - Van Belle, Sarah

AU - Lommerts, Janny E.

AU - Hamzavi, Iltefat

AU - Harris, John E.

AU - Eleftheriadou, Viktoria

AU - Esmat, Samia

AU - Kang, Hee Young

AU - Kumarasinghe, Prasad

AU - Lan, Cheng Che E.

AU - Parsad, Davinder

AU - Raboobee, Noufal

AU - Flora Xiang, Leihong

AU - Suzuki, Tamio

AU - Prinsen, Cecilia A.

AU - Taieb, Alain

AU - Picardo, Mauro

AU - Speeckaert, Reinhart

AU - Anbar, Tag

AU - Anbar, Mohamed

AU - Benzekri, Laïla

AU - Böhm, Markus

AU - Castro, Caïo

AU - Cestari, Tania

AU - Gauthier, Yvon

AU - Gnarra, Maria

AU - Hinojosa, Jorge

AU - Jung, Min Bae

AU - Katayama, Ichiro

AU - Kim, Ki Ho

AU - Eric Lan, Cheng Che

AU - Lee, Seung Chung

AU - Le Poole, Caroline

AU - Lim, Henry

AU - Moretti, Silvia

AU - Seneschal, Julien

AU - Spritz, Richard

AU - van Geel, Nanja

AU - Xiang, Flora

PY - 2019

Y1 - 2019

N2 - Currently, vitiligo lacks a validated Physician Global Assessment (PGA) for disease extent. This PGA can be used to stratify and interpret the numeric scores obtained by the Vitiligo Extent Score (VES). We investigated the interrater reliability of a 5-point PGA scale during an international vitiligo workshop. Vitiligo experts from five different continents rated photographs of non-segmental vitiligo patients with varying degrees of extent with the PGA score. Good interrater agreements (intraclass correlation coefficient >0.6) were observed between the raters overall and within each continent. All hypotheses to evaluate construct validity were confirmed. Median VES values per category were for limited 1.10 [IQR: 0.21–1.67], moderate 3.17 [IQR: 1.75–6.21], extensive 9.58 [IQR: 6.21–13.03] and very extensive 42.67 [IQR: 21.20–42.67]. Defined categories for vitiligo extent can be valuable for inclusion criteria and may impact future reimbursement criteria.

AB - Currently, vitiligo lacks a validated Physician Global Assessment (PGA) for disease extent. This PGA can be used to stratify and interpret the numeric scores obtained by the Vitiligo Extent Score (VES). We investigated the interrater reliability of a 5-point PGA scale during an international vitiligo workshop. Vitiligo experts from five different continents rated photographs of non-segmental vitiligo patients with varying degrees of extent with the PGA score. Good interrater agreements (intraclass correlation coefficient >0.6) were observed between the raters overall and within each continent. All hypotheses to evaluate construct validity were confirmed. Median VES values per category were for limited 1.10 [IQR: 0.21–1.67], moderate 3.17 [IQR: 1.75–6.21], extensive 9.58 [IQR: 6.21–13.03] and very extensive 42.67 [IQR: 21.20–42.67]. Defined categories for vitiligo extent can be valuable for inclusion criteria and may impact future reimbursement criteria.

KW - body surface area

KW - extent

KW - global assessment

KW - outcome measure

KW - severity

KW - vitiligo

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U2 - 10.1111/pcmr.12784

DO - 10.1111/pcmr.12784

M3 - Article

C2 - 30945409

AN - SCOPUS:85065641370

SN - 1755-1471

VL - 32

SP - 728

EP - 733

JO - Pigment Cell and Melanoma Research

JF - Pigment Cell and Melanoma Research

IS - 5

ER -

Validation of a physician global assessment tool for vitiligo extent: Results of an international vitiligo expert meeting

Abstract

Keywords

ASJC Scopus subject areas

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