Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice

Medicine & Life Sciences

• Nanophthalmos 1 100%
• Retinal Degeneration 53%
• Myelin Sheath 44%
• Hyperopia 35%
• Frameshift Mutation 21%
• Refractive Errors 20%
• Retinal Pigment Epithelium 19%
• Eye 16%
• Knockout Mice 15%
• Genes 13%
• Angle Closure Glaucoma 11%
• Amblyopia 10%
• Exome 10%
• Strabismus 10%
• Growth and Development 8%
• Information Storage and Retrieval 7%
• Ocular Vision 7%
• Exons 7%
• Anatomy 7%
• Transcription Factors 6%
• RNA 6%
• Membranes 5%
• Child 3%
• Proteins 3%

Agriculture & Biology

• retinal degeneration 67%
• myelin sheath 50%
• mice 25%
• frameshift mutation 23%
• eyes 20%
• epithelium 14%
• pigments 13%
• glaucoma 12%
• genes 12%
• loci 10%
• messenger RNA 8%
• exons 7%
• linkage (genetics) 7%
• growth and development 7%
• transcription factors 6%
• proteins 2%

Earth & Environmental Sciences

• gene 33%
• mutation 21%
• pigment 20%
• growth and development 12%
• anatomy 11%
• RNA 11%
• cleavage 10%
• family 7%
• protein 7%
• membrane 7%
• loss 5%