Venous occlusion to the lower limb attenuates vasoconstriction in the nonexercised limb during posthandgrip muscle ischemia

K. Tokizawa, M. Mizuno, Y. Nakamura, I. Muraoka

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We investigated the effects of increases in calf volume on cardiovascular responses during handgrip (HG) exercise and post-HG exercise muscle ischemia (PEMI). Seven subjects completed two trials: one control (no occlusion) and one venous occlusion (VO) session. Both trials included a baseline measurement followed by 15 min of rest (REST), 2 min of HG, and 2 min of PEMI. VO was applied at 100 mmHg via cuffs placed around both distal thighs during REST, HG, and PEMI. Mean arterial pressure, heart rate, forearm blood flow (FBF) in the nonexercised arm, and forearm vascular resistance (FVR) in the nonexercised arm (FVR) were measured. During REST and HG, there were no significant differences between trials in all parameters. During PEMI in the control trial, mean arterial pressure and FVR were significantly greater and FBF was significantly lower than baseline values (P < 0.05 for each). In contrast, in the VO trial, FBF and FVR responses were different from control responses. In the VO trial, FBF was significantly greater than in the control trial (4.7 ± 0.5 vs. 2.5 ± 0.3 ml·100 ml-1·min-1, P < 0.05) and FVR was significantly lower (28.0 ± 4.8 vs. 49.1 ± 4.6 units, respectively, P < 0.05). These results indicate that increases in vascular resistance in the nonexercised limb induced by activation of the muscle chemoreflex can be attenuated by increases in calf volume.

Original languageEnglish (US)
Pages (from-to)981-984
Number of pages4
JournalJournal of Applied Physiology
Volume96
Issue number3
DOIs
StatePublished - Mar 2004

Fingerprint

Vasoconstriction
Forearm
Lower Extremity
Ischemia
Extremities
Vascular Resistance
Muscles
Arterial Pressure
Arm
Thigh
Heart Rate

Keywords

  • Blood flow
  • Calf volume
  • Muscle chemoreflex
  • Vascular resistance

ASJC Scopus subject areas

  • Physiology
  • Endocrinology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Venous occlusion to the lower limb attenuates vasoconstriction in the nonexercised limb during posthandgrip muscle ischemia. / Tokizawa, K.; Mizuno, M.; Nakamura, Y.; Muraoka, I.

In: Journal of Applied Physiology, Vol. 96, No. 3, 03.2004, p. 981-984.

Research output: Contribution to journalArticle

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