Venous thrombosis: Clinical and experimental MR imaging

W. A. Erdman, J. C. Weinreb, J. M. Cohen, L. M. Buja, C. Chaney, Ronald M Peshock

Research output: Contribution to journalArticle

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Abstract

Five venous thrombi were induced in the external jugular veins of three laboratory dogs, and were repeatedly imaged over 3 weeks using a 0.35-T magnetic resonance (MR) imager. MR magnitude and phase images, T1 and T2 relaxation times, venography, and histologic sections of these thrombi were evaluated to determine the changes in appearance on MR images with time. Venous thrombi appeared hyperintense compared with muscle on both relatively T1- and T2-weighted spin-echo sequences regardless of the age of the clot. Organization of the thrombus beyond 1 week was manifested as increased prominence of flow signal void in and around the clot. Distinction between intraluminal thrombus and flow-related artifacts was aided by phase image reconstruction. Nineteen venous thrombi locations in 13 patients revealed an MR appearance similar to that of the experimental animal model. Three patients (six thrombi locations) had serial examinations over 4 weeks. No significant change in thrombus signal characteristics was noted with time. It is concluded that MR imaging at 0.35 T cannot be used to predict the age of thrombus (up to 3 weeks) but may be helpful in following its resolution.

Original languageEnglish (US)
Pages (from-to)233-238
Number of pages6
JournalRadiology
Volume161
Issue number1
StatePublished - 1986

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Venous Thrombosis
Thrombosis
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Computer-Assisted Image Processing
Phlebography
Jugular Veins
Artifacts
Animal Models
Dogs
Muscles

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Erdman, W. A., Weinreb, J. C., Cohen, J. M., Buja, L. M., Chaney, C., & Peshock, R. M. (1986). Venous thrombosis: Clinical and experimental MR imaging. Radiology, 161(1), 233-238.

Venous thrombosis : Clinical and experimental MR imaging. / Erdman, W. A.; Weinreb, J. C.; Cohen, J. M.; Buja, L. M.; Chaney, C.; Peshock, Ronald M.

In: Radiology, Vol. 161, No. 1, 1986, p. 233-238.

Research output: Contribution to journalArticle

Erdman, WA, Weinreb, JC, Cohen, JM, Buja, LM, Chaney, C & Peshock, RM 1986, 'Venous thrombosis: Clinical and experimental MR imaging', Radiology, vol. 161, no. 1, pp. 233-238.
Erdman WA, Weinreb JC, Cohen JM, Buja LM, Chaney C, Peshock RM. Venous thrombosis: Clinical and experimental MR imaging. Radiology. 1986;161(1):233-238.
Erdman, W. A. ; Weinreb, J. C. ; Cohen, J. M. ; Buja, L. M. ; Chaney, C. ; Peshock, Ronald M. / Venous thrombosis : Clinical and experimental MR imaging. In: Radiology. 1986 ; Vol. 161, No. 1. pp. 233-238.
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