Abstract
The ventilatory response to exercise below ventilatory threshold (VTh) increases with aging, whereas above VTh the ventilatory response declines only slightly. We wondered whether this same ventilatory response would be observed in older runners. We also wondered whether their ventilatory response to exercise while breathing He-O2 or inspired CO2 would be different. To investigate, we studied 12 seniors (63 ± 4 yr; 10 men, 2 women) who exercised regularly (5 ± 1 days/Wk, 29 ± 11 mi/wk, 16 ± 6 yr). Each subject performed graded cycle ergometry to exhaustion on 3 separate days, breathing either room air, 3% inspired CO2, or a heliox mixture (79% He and 21% O2). The ventilatory response to exercise below VTh was 0.35 ± 0.06 l·min-1·W-1 and above VTh was 0.66 ± 0.10 l·min-1·W-1. He-O2 breathing increased (P < 0.05) the ventilatory response to exercise both below (0.40 ± 0.12 l·min-1·W-1) and above VTh (0.81 ± 0.10 l·min-1·W-1). Inspired CO2 increased (P < 0.001) the ventilatory response to exercise only below VTh (0.44 ± 0.10 l·min-1·W-1). The ventilatory responses to exercise with room air, He-O2, and CO2 breathing of these fit runners were similar to those observed earlier in older sedentary individuals. These data suggest that the ventilatory response to exercise of these senior runners is adequate to support their greater exercise capacity and that exercise training does not alter the ventilatory response to exercise with He-O2 or inspired CO2 breathing.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 685-693 |
| Number of pages | 9 |
| Journal | Journal of Applied Physiology |
| Volume | 94 |
| Issue number | 2 |
| State | Published - Feb 1 2003 |
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Keywords
- Control of breathing during exercise
- Ventilatory responses to loaded and unloaded breathing
- Work of breathing during exercise
ASJC Scopus subject areas
- Physiology
- Endocrinology
- Orthopedics and Sports Medicine
- Physical Therapy, Sports Therapy and Rehabilitation
Cite this
Ventilatory response to exercise in aged runners breathing He-O2 or inspired CO2 . / Babb, T. G.; DeLorey, Darren S.; Wyrick, Brenda L.
In: Journal of Applied Physiology, Vol. 94, No. 2, 01.02.2003, p. 685-693.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ventilatory response to exercise in aged runners breathing He-O2 or inspired CO2
AU - Babb, T. G.
AU - DeLorey, Darren S.
AU - Wyrick, Brenda L.
PY - 2003/2/1
Y1 - 2003/2/1
N2 - The ventilatory response to exercise below ventilatory threshold (VTh) increases with aging, whereas above VTh the ventilatory response declines only slightly. We wondered whether this same ventilatory response would be observed in older runners. We also wondered whether their ventilatory response to exercise while breathing He-O2 or inspired CO2 would be different. To investigate, we studied 12 seniors (63 ± 4 yr; 10 men, 2 women) who exercised regularly (5 ± 1 days/Wk, 29 ± 11 mi/wk, 16 ± 6 yr). Each subject performed graded cycle ergometry to exhaustion on 3 separate days, breathing either room air, 3% inspired CO2, or a heliox mixture (79% He and 21% O2). The ventilatory response to exercise below VTh was 0.35 ± 0.06 l·min-1·W-1 and above VTh was 0.66 ± 0.10 l·min-1·W-1. He-O2 breathing increased (P < 0.05) the ventilatory response to exercise both below (0.40 ± 0.12 l·min-1·W-1) and above VTh (0.81 ± 0.10 l·min-1·W-1). Inspired CO2 increased (P < 0.001) the ventilatory response to exercise only below VTh (0.44 ± 0.10 l·min-1·W-1). The ventilatory responses to exercise with room air, He-O2, and CO2 breathing of these fit runners were similar to those observed earlier in older sedentary individuals. These data suggest that the ventilatory response to exercise of these senior runners is adequate to support their greater exercise capacity and that exercise training does not alter the ventilatory response to exercise with He-O2 or inspired CO2 breathing.
AB - The ventilatory response to exercise below ventilatory threshold (VTh) increases with aging, whereas above VTh the ventilatory response declines only slightly. We wondered whether this same ventilatory response would be observed in older runners. We also wondered whether their ventilatory response to exercise while breathing He-O2 or inspired CO2 would be different. To investigate, we studied 12 seniors (63 ± 4 yr; 10 men, 2 women) who exercised regularly (5 ± 1 days/Wk, 29 ± 11 mi/wk, 16 ± 6 yr). Each subject performed graded cycle ergometry to exhaustion on 3 separate days, breathing either room air, 3% inspired CO2, or a heliox mixture (79% He and 21% O2). The ventilatory response to exercise below VTh was 0.35 ± 0.06 l·min-1·W-1 and above VTh was 0.66 ± 0.10 l·min-1·W-1. He-O2 breathing increased (P < 0.05) the ventilatory response to exercise both below (0.40 ± 0.12 l·min-1·W-1) and above VTh (0.81 ± 0.10 l·min-1·W-1). Inspired CO2 increased (P < 0.001) the ventilatory response to exercise only below VTh (0.44 ± 0.10 l·min-1·W-1). The ventilatory responses to exercise with room air, He-O2, and CO2 breathing of these fit runners were similar to those observed earlier in older sedentary individuals. These data suggest that the ventilatory response to exercise of these senior runners is adequate to support their greater exercise capacity and that exercise training does not alter the ventilatory response to exercise with He-O2 or inspired CO2 breathing.
KW - Control of breathing during exercise
KW - Ventilatory responses to loaded and unloaded breathing
KW - Work of breathing during exercise
UR - http://www.scopus.com/inward/record.url?scp=0037310314&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037310314&partnerID=8YFLogxK
M3 - Article
C2 - 12531912
AN - SCOPUS:0037310314
VL - 94
SP - 685
EP - 693
JO - Journal of Applied Physiology
JF - Journal of Applied Physiology
SN - 0161-7567
IS - 2
ER -