Verrucous carcinoma of the endometrium: Case history, pathologic findings, brief review of literature and discussion

Diego Illanes, Jerry Broman, Bruce Meyer, Daniel Kredentser, Timothy McElrath, Patrick Timmins

Research output: Contribution to journalArticle

13 Scopus citations


Background.: Verrucous carcinoma is a rare condition. A defined disease of the oral cavity, larynx, esophagus, skin, vulva, vagina and cervix. But a verrucous carcinoma arising from the endometrium without evidence of cervical malignancy or endometrial adenocarcinoma is extremely rare. Case.: A 67-year-old G2P2 menopausal patient that was referred for consultation 1 year after presenting with vaginal bleeding to her gynecologist who subsequently underwent several endometrial biopsies where the pathological findings were repetitively similar: papillary squamous proliferation, cytologically bland with low mitotic activity but extensive proliferation. A hysterectomy with bilateral salpingo-oophorectomy was performed. The final histologic examination revealed a squamous cell carcinoma of endometrium, verrucous and well differentiated, and there was no cervical invasion identified. Conclusion.: This is a rare form of endometrial cancer with apparent favorable prognosis that must be considered when squamous cells are identified on endometrial samplings.

Original languageEnglish (US)
Pages (from-to)375-377
Number of pages3
JournalGynecologic Oncology
Issue number2
Publication statusPublished - Aug 2006



  • Endometrium
  • Hyperkeratosis
  • Squamous cell carcinoma
  • Squamous papilloma
  • Verrucous carcinoma

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

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