Vertebral artery-posteroinferior cerebellar artery aneurysms

Clinical and lower cranial nerve outcomes in 52 patients

Hisham Al-Khayat, Haitham Al-Khayat, Joseph Beshay, David Manner, Jonathan White, Duke S. Samson

Research output: Contribution to journalArticle

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Abstract

OBJECTIVE: To identify factors predictive of postoperative lower cranial nerve palsy (LCNP) among patients undergoing surgery for vertebral artery (VA)- posteroinferior cerebellar artery (PICA) aneurysms. The natural history of this LCNP is defined, and its effect on postoperative patient course is analyzed. No similar study has been described in the literature. METHODS: Fifty-two patients with VA-PICA aneurysms, who were treated surgically between 1996 and 2002, were retrospectively studied to identify factors contributing to postoperative LCNP. The effect of LCNP on intensive care unit stay and development of nosocomial pneumonia also was analyzed. All analyses were performed with Fisher's exact test. RESULTS: Postoperative LCNP occurred in 25 patients (48.1%) with VA-PICA aneurysms. Of the factors investigated, the use of temporary or total occlusion was associated with increased incidence of postoperative LCNP (P < 0.001). The average length of stay in the intensive care unit was 13.8 days for patients with LCNP defined as moderate to severe, compared with 7.92 days for patients with LCNP defined as none or mild (P = 0.0014). Nosocomial pneumonia occurred only in patients with moderate to severe LCNP (P = 0.022). Postoperative LCNP resolved completely within 3 months in 12 patients (48%) and within 6 months in 19 patients (76%). CONCLUSION: The results of this study can help to identify the effect and natural history of LCNP after surgical clipping of VA-PICA aneurysms. This information may assist neurosurgeons in expediting treatment, decrease the cost and length of hospital stays, and result in improved outcomes.

Original languageEnglish (US)
Pages (from-to)2-10
Number of pages9
JournalNeurosurgery
Volume56
Issue number1
DOIs
StatePublished - Jan 2005

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Cranial Nerve Diseases
Vertebral Artery
Cranial Nerves
Aneurysm
Arteries
Length of Stay
Natural History
Intensive Care Units
Pneumonia
Health Care Costs

Keywords

  • Glasgow Outcome Scale
  • Lower cranial nerve palsy
  • Subarachnoid hemorrhage
  • Vertebral artery-posteroinferior cerebellar artery aneurysm

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Vertebral artery-posteroinferior cerebellar artery aneurysms : Clinical and lower cranial nerve outcomes in 52 patients. / Al-Khayat, Hisham; Al-Khayat, Haitham; Beshay, Joseph; Manner, David; White, Jonathan; Samson, Duke S.

In: Neurosurgery, Vol. 56, No. 1, 01.2005, p. 2-10.

Research output: Contribution to journalArticle

Al-Khayat, Hisham ; Al-Khayat, Haitham ; Beshay, Joseph ; Manner, David ; White, Jonathan ; Samson, Duke S. / Vertebral artery-posteroinferior cerebellar artery aneurysms : Clinical and lower cranial nerve outcomes in 52 patients. In: Neurosurgery. 2005 ; Vol. 56, No. 1. pp. 2-10.
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