Viral infections in HIV disease

Wei Su, Cindy Berthelot, Clay J Cockerell

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

DEFINITION/OVERVIEW Acute HIV infection, also known as acute retroviral syndrome (ARS) and seroconversion illness, is the period from the initial infection with HIV to complete seroconversion. It is often subclinical and asymptomatic, and therefore may escape diagnosis. Symptomatic ARS is a transient illness that is associated with robust HIV replication followed by an expansive immunologic response to the virus.1 The estimated incidence of symptomatic primary HIV infection ranges from 25% to 75%.2,3 ARS has been described in all populations at risk for HIV infection: Homosexual men, heterosexual men and women, recipients of contaminated blood, recipients of organs from infected donors, and those acquiring HIV from accidental occupational exposure and contaminated body fluids.4 Acute HIV infection is a period of extreme infectiousness, and the occurrence and severity of symptoms during ARS may correlate with the severity of clinical decline. It has been shown that early identification and treatment of patients with ARS may preserve immune function. Therefore, timely recognition of the ARS is imperative for patients and for public health as it allows for early initiation of antiviral therapy and prevention of subsequent transmission.

Original languageEnglish (US)
Title of host publicationCutaneous Manifestations of HIV Disease
PublisherCRC Press
Pages11-37
Number of pages27
ISBN (Electronic)9781840766042
ISBN (Print)9781840761429
DOIs
StatePublished - Jan 1 2012

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Virus Diseases
HIV Infections
HIV
Heterosexuality
Occupational Exposure
Antiviral Agents
Acute Retroviral Syndrome
Public Health
Tissue Donors
Incidence
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Su, W., Berthelot, C., & Cockerell, C. J. (2012). Viral infections in HIV disease. In Cutaneous Manifestations of HIV Disease (pp. 11-37). CRC Press. https://doi.org/10.1201/b15910

Viral infections in HIV disease. / Su, Wei; Berthelot, Cindy; Cockerell, Clay J.

Cutaneous Manifestations of HIV Disease. CRC Press, 2012. p. 11-37.

Research output: Chapter in Book/Report/Conference proceedingChapter

Su, W, Berthelot, C & Cockerell, CJ 2012, Viral infections in HIV disease. in Cutaneous Manifestations of HIV Disease. CRC Press, pp. 11-37. https://doi.org/10.1201/b15910
Su W, Berthelot C, Cockerell CJ. Viral infections in HIV disease. In Cutaneous Manifestations of HIV Disease. CRC Press. 2012. p. 11-37 https://doi.org/10.1201/b15910
Su, Wei ; Berthelot, Cindy ; Cockerell, Clay J. / Viral infections in HIV disease. Cutaneous Manifestations of HIV Disease. CRC Press, 2012. pp. 11-37
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