Virulence determinants for Vibrio parahaemolyticus infection

Lingling Zhang, Kim Orth

Research output: Contribution to journalReview article

85 Scopus citations

Abstract

Vibrio parahaemolyticus is a marine microorganism that causes acute gastroenteritis associated with the consumption of contaminated raw or under cooked seafood. During infection, the bacterium utilizes a wide variety of virulence factors, including adhesins, toxins and type III secretion systems, to cause both cytotoxicity in cultured cells and enterotoxicity in animal models. Herein, we describe recent discoveries on the regulation and characterization of the virulence factors from V. para. Determining how this bacterial pathogen uses virulence factors to mediate pathogenicity improves our understanding of V. para. infections and more generally, host-pathogen interactions.

Original languageEnglish (US)
Pages (from-to)70-77
Number of pages8
JournalCurrent Opinion in Microbiology
Volume16
Issue number1
DOIs
StatePublished - Feb 1 2013

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ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases

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