TY - JOUR
T1 - Visible Light Induced Brønsted Acid Assisted Pd-Catalyzed Alkyl Heck Reaction of Diazo Compounds and N-Tosylhydrazones
AU - Zhang, Ziyan
AU - Kvasovs, Nikita
AU - Dubrovina, Anastasiia
AU - Gevorgyan, Vladimir
N1 - Publisher Copyright:
© 2021 Wiley-VCH GmbH
PY - 2022/1/3
Y1 - 2022/1/3
N2 - A mild visible light-induced palladium-catalyzed alkyl Heck reaction of diazo compounds and N-tosylhydrazones is reported. A broad range of vinyl arenes and heteroarenes with high functional group tolerance, as well as a range of different diazo compounds, can efficiently undergo this transformation. This method features Brønsted acid-assisted generation of hybrid palladium C(sp3)-centered radical intermediate, which allowed for new selective C−H functionalization protocol.
AB - A mild visible light-induced palladium-catalyzed alkyl Heck reaction of diazo compounds and N-tosylhydrazones is reported. A broad range of vinyl arenes and heteroarenes with high functional group tolerance, as well as a range of different diazo compounds, can efficiently undergo this transformation. This method features Brønsted acid-assisted generation of hybrid palladium C(sp3)-centered radical intermediate, which allowed for new selective C−H functionalization protocol.
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U2 - 10.1002/anie.202110924
DO - 10.1002/anie.202110924
M3 - Article
C2 - 34706124
AN - SCOPUS:85119859520
SN - 1433-7851
VL - 61
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 1
M1 - e202110924
ER -