Visualization and quantification of renal R2* changes during water diuresis

Chun S. Zuo; Neil M. Rofsky; Houman Mahallati; Jeongsik Yu; Ming Zhang; Scott Gilbert; Franklin H. Epstein

doi:10.1002/jmri.10314

Visualization and quantification of renal R2* changes during water diuresis

Chun S. Zuo, Neil M. Rofsky, Houman Mahallati, Jeongsik Yu, Ming Zhang, Scott Gilbert, Franklin H. Epstein

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Purpose: To refine and evaluate methods for analysis of renal blood oxygenation level dependent (BOLD) MRI data. Materials and Methods: Color R2* maps and regions-of-interest (ROIs) on the borderline between cortex and medulla were applied to renal BOLD MRI data of a group of 13 young female subjects. Results: The distribution of R2* within the kidneys was heterogeneous and the response of human kidneys to water diuresis was patchy. R2* values at the cortico-medullary border region have a smaller variation than in wider cortical or medullary regions and are sensitive to physiological changes produced by water diuresis. Conclusion: These methods provide improved visualization of the regional distribution of R2* and its variations and more precise quantification of the changes in renal R2* produced by water diuresis.

Original language	English (US)
Pages (from-to)	676-682
Number of pages	7
Journal	Journal of Magnetic Resonance Imaging
Volume	17
Issue number	6
DOIs	https://doi.org/10.1002/jmri.10314
State	Published - Jun 1 2003

Keywords

BOLD MRI
Cortico-medullary borderline
Map
R2*
ROI
Tenal oxygenation

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1002/jmri.10314

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title = "Visualization and quantification of renal R2* changes during water diuresis",

abstract = "Purpose: To refine and evaluate methods for analysis of renal blood oxygenation level dependent (BOLD) MRI data. Materials and Methods: Color R2* maps and regions-of-interest (ROIs) on the borderline between cortex and medulla were applied to renal BOLD MRI data of a group of 13 young female subjects. Results: The distribution of R2* within the kidneys was heterogeneous and the response of human kidneys to water diuresis was patchy. R2* values at the cortico-medullary border region have a smaller variation than in wider cortical or medullary regions and are sensitive to physiological changes produced by water diuresis. Conclusion: These methods provide improved visualization of the regional distribution of R2* and its variations and more precise quantification of the changes in renal R2* produced by water diuresis.",

keywords = "BOLD MRI, Cortico-medullary borderline, Map, R2*, ROI, Tenal oxygenation",

author = "Zuo, {Chun S.} and Rofsky, {Neil M.} and Houman Mahallati and Jeongsik Yu and Ming Zhang and Scott Gilbert and Epstein, {Franklin H.}",

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T1 - Visualization and quantification of renal R2* changes during water diuresis

AU - Zuo, Chun S.

AU - Rofsky, Neil M.

AU - Mahallati, Houman

AU - Yu, Jeongsik

AU - Zhang, Ming

AU - Gilbert, Scott

AU - Epstein, Franklin H.

PY - 2003/6/1

Y1 - 2003/6/1

N2 - Purpose: To refine and evaluate methods for analysis of renal blood oxygenation level dependent (BOLD) MRI data. Materials and Methods: Color R2* maps and regions-of-interest (ROIs) on the borderline between cortex and medulla were applied to renal BOLD MRI data of a group of 13 young female subjects. Results: The distribution of R2* within the kidneys was heterogeneous and the response of human kidneys to water diuresis was patchy. R2* values at the cortico-medullary border region have a smaller variation than in wider cortical or medullary regions and are sensitive to physiological changes produced by water diuresis. Conclusion: These methods provide improved visualization of the regional distribution of R2* and its variations and more precise quantification of the changes in renal R2* produced by water diuresis.

AB - Purpose: To refine and evaluate methods for analysis of renal blood oxygenation level dependent (BOLD) MRI data. Materials and Methods: Color R2* maps and regions-of-interest (ROIs) on the borderline between cortex and medulla were applied to renal BOLD MRI data of a group of 13 young female subjects. Results: The distribution of R2* within the kidneys was heterogeneous and the response of human kidneys to water diuresis was patchy. R2* values at the cortico-medullary border region have a smaller variation than in wider cortical or medullary regions and are sensitive to physiological changes produced by water diuresis. Conclusion: These methods provide improved visualization of the regional distribution of R2* and its variations and more precise quantification of the changes in renal R2* produced by water diuresis.

KW - BOLD MRI

KW - Cortico-medullary borderline

KW - Map

KW - R2

KW - ROI

KW - Tenal oxygenation

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Visualization and quantification of renal R2* changes during water diuresis

Abstract

Keywords

ASJC Scopus subject areas

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