Abstract
This article considers the treatment plan optimization problem for Volumetric Modulated Arc Therapy (VMAT) with constant gantry speed and dose rate (VMATc). In particular, we consider the simultaneous optimization of multi-leaf collimator leaf positions and a constant gantry speed and dose rate. We propose a heuristic framework for (approximately) solving this optimization problem that is based on hierarchical decomposition. Specifically, an iterative algorithm is used to heuristically optimize dose rate and gantry speed selection, where at every iteration a leaf position optimization subproblem is solved, also heuristically, to find a high-quality plan corresponding to a given dose rate and gantry speed. We apply our framework to clinical patient cases, and compare the resulting VMATc plans to idealized IMRT, as well as full VMAT plans. Our results suggest that VMATc is capable of producing treatment plans of comparable quality to VMAT, albeit at the expense of long computation time and generally higher total monitor units.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2955-2979 |
| Number of pages | 25 |
| Journal | Physics in Medicine and Biology |
| Volume | 60 |
| Issue number | 7 |
| DOIs | |
| State | Published - Apr 7 2015 |
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Keywords
- constant dose rate
- constant gantry speed
- radiation therapy
- treatment plan optimization
- volumetric modulated arc therapy
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Radiological and Ultrasound Technology
Cite this
VMATc : VMAT with constant gantry speed and dose rate. / Peng, Fei; Jiang, Steve B.; Romeijn, H. Edwin; Epelman, Marina A.
In: Physics in Medicine and Biology, Vol. 60, No. 7, 07.04.2015, p. 2955-2979.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - VMATc
T2 - VMAT with constant gantry speed and dose rate
AU - Peng, Fei
AU - Jiang, Steve B.
AU - Romeijn, H. Edwin
AU - Epelman, Marina A.
PY - 2015/4/7
Y1 - 2015/4/7
N2 - This article considers the treatment plan optimization problem for Volumetric Modulated Arc Therapy (VMAT) with constant gantry speed and dose rate (VMATc). In particular, we consider the simultaneous optimization of multi-leaf collimator leaf positions and a constant gantry speed and dose rate. We propose a heuristic framework for (approximately) solving this optimization problem that is based on hierarchical decomposition. Specifically, an iterative algorithm is used to heuristically optimize dose rate and gantry speed selection, where at every iteration a leaf position optimization subproblem is solved, also heuristically, to find a high-quality plan corresponding to a given dose rate and gantry speed. We apply our framework to clinical patient cases, and compare the resulting VMATc plans to idealized IMRT, as well as full VMAT plans. Our results suggest that VMATc is capable of producing treatment plans of comparable quality to VMAT, albeit at the expense of long computation time and generally higher total monitor units.
AB - This article considers the treatment plan optimization problem for Volumetric Modulated Arc Therapy (VMAT) with constant gantry speed and dose rate (VMATc). In particular, we consider the simultaneous optimization of multi-leaf collimator leaf positions and a constant gantry speed and dose rate. We propose a heuristic framework for (approximately) solving this optimization problem that is based on hierarchical decomposition. Specifically, an iterative algorithm is used to heuristically optimize dose rate and gantry speed selection, where at every iteration a leaf position optimization subproblem is solved, also heuristically, to find a high-quality plan corresponding to a given dose rate and gantry speed. We apply our framework to clinical patient cases, and compare the resulting VMATc plans to idealized IMRT, as well as full VMAT plans. Our results suggest that VMATc is capable of producing treatment plans of comparable quality to VMAT, albeit at the expense of long computation time and generally higher total monitor units.
KW - constant dose rate
KW - constant gantry speed
KW - radiation therapy
KW - treatment plan optimization
KW - volumetric modulated arc therapy
UR - http://www.scopus.com/inward/record.url?scp=84925667214&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84925667214&partnerID=8YFLogxK
U2 - 10.1088/0031-9155/60/7/2955
DO - 10.1088/0031-9155/60/7/2955
M3 - Article
C2 - 25789937
AN - SCOPUS:84925667214
VL - 60
SP - 2955
EP - 2979
JO - Physics in Medicine and Biology
JF - Physics in Medicine and Biology
SN - 0031-9155
IS - 7
ER -