Abstract
Bilateral lesions of the VMN virtually eliminate estrogen-progesterone stimulated lordosis in the spayed female rat. The present paper demonstrates that some recovery in lordosis is possible following treatment with pergolide mesylate, a potent long acting dopamine agonist. Chronic administration of pergolide mesylate in combination with estrogen and progesterone resulted in significant recovery of lordosis in VMN lesioned female rats. The magnitude of recovery was related to the duration and/or dose of pergolide.
Original language | English (US) |
---|---|
Pages (from-to) | 745-748 |
Number of pages | 4 |
Journal | Physiology and Behavior |
Volume | 31 |
Issue number | 6 |
DOIs | |
State | Published - Dec 1983 |
Externally published | Yes |
Keywords
- Lordosis behavior
- Pergolide mesylate
- VMN lesions
ASJC Scopus subject areas
- Experimental and Cognitive Psychology
- Behavioral Neuroscience