VMN lesion deficits in lordosis: Partial reversal with pergolide mesylate

Dana Mathews; Susan B. Greene; Eileen M. Hollingsworth

doi:10.1016/0031-9384(83)90269-X

VMN lesion deficits in lordosis: Partial reversal with pergolide mesylate

Dana Mathews, Susan B. Greene, Eileen M. Hollingsworth

Research output: Contribution to journal › Article

8 Scopus citations

Abstract

Bilateral lesions of the VMN virtually eliminate estrogen-progesterone stimulated lordosis in the spayed female rat. The present paper demonstrates that some recovery in lordosis is possible following treatment with pergolide mesylate, a potent long acting dopamine agonist. Chronic administration of pergolide mesylate in combination with estrogen and progesterone resulted in significant recovery of lordosis in VMN lesioned female rats. The magnitude of recovery was related to the duration and/or dose of pergolide.

Original language	English (US)
Pages (from-to)	745-748
Number of pages	4
Journal	Physiology and Behavior
Volume	31
Issue number	6
DOIs	https://doi.org/10.1016/0031-9384(83)90269-X
State	Published - Dec 1983
Externally published	Yes

Keywords

Lordosis behavior
Pergolide mesylate
VMN lesions

ASJC Scopus subject areas

Experimental and Cognitive Psychology
Behavioral Neuroscience

Access to Document

10.1016/0031-9384(83)90269-X

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Mathews, D., Greene, S. B., & Hollingsworth, E. M. (1983). VMN lesion deficits in lordosis: Partial reversal with pergolide mesylate. Physiology and Behavior, 31(6), 745-748. https://doi.org/10.1016/0031-9384(83)90269-X

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