Volumetric fat-water separated T2-weighted MRI

Shreyas S. Vasanawala, Ananth J. Madhuranthakam, Ramesh Venkatesan, Arvind Sonik, Peng Lai, Anja C S Brau

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Pediatric body MRI exams often cover multiple body parts, making the development of broadly applicable protocols and obtaining uniform fat suppression a challenge. Volumetric T2 imaging with Dixon-type fat-water separation might address this challenge, but it is a lengthy process. Objective: We develop and evaluate a faster two-echo approach to volumetric T2 imaging with fat-water separation. Materials and methods: A volumetric spin-echo sequence was modified to include a second shifted echo so two image sets are acquired. A region-growing reconstruction approach was developed to decompose separate water and fat images. Twenty-six children were recruited with IRB approval and informed consent. Fat-suppression quality was graded by two pediatric radiologists and compared against conventional fat-suppressed fast spin-echo T2-W images. Additionally, the value of in- and opposed-phase images was evaluated. Results: Fat suppression on volumetric images had high quality in 96% of cases (95% confidence interval of 80-100%) and were preferred over or considered equivalent to conventional two-dimensional fat-suppressed FSE T2 imaging in 96% of cases (95% confidence interval of 78-100%). In- and opposed-phase images had definite value in 12% of cases. Conclusion: Volumetric fat-water separated T2-weighted MRI is feasible and is likely to yield improved fat suppression over conventional fat-suppressed T2-weighted imaging.

Original languageEnglish (US)
Pages (from-to)875-883
Number of pages9
JournalPediatric Radiology
Volume41
Issue number7
DOIs
StatePublished - Jul 2011

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Fats
Water
Confidence Intervals
Pediatrics
Research Ethics Committees
Informed Consent
Human Body

Keywords

  • Fat suppression
  • MRI
  • Pediatric
  • T2

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Pediatrics, Perinatology, and Child Health

Cite this

Vasanawala, S. S., Madhuranthakam, A. J., Venkatesan, R., Sonik, A., Lai, P., & Brau, A. C. S. (2011). Volumetric fat-water separated T2-weighted MRI. Pediatric Radiology, 41(7), 875-883. https://doi.org/10.1007/s00247-010-1963-5

Volumetric fat-water separated T2-weighted MRI. / Vasanawala, Shreyas S.; Madhuranthakam, Ananth J.; Venkatesan, Ramesh; Sonik, Arvind; Lai, Peng; Brau, Anja C S.

In: Pediatric Radiology, Vol. 41, No. 7, 07.2011, p. 875-883.

Research output: Contribution to journalArticle

Vasanawala, SS, Madhuranthakam, AJ, Venkatesan, R, Sonik, A, Lai, P & Brau, ACS 2011, 'Volumetric fat-water separated T2-weighted MRI', Pediatric Radiology, vol. 41, no. 7, pp. 875-883. https://doi.org/10.1007/s00247-010-1963-5
Vasanawala, Shreyas S. ; Madhuranthakam, Ananth J. ; Venkatesan, Ramesh ; Sonik, Arvind ; Lai, Peng ; Brau, Anja C S. / Volumetric fat-water separated T2-weighted MRI. In: Pediatric Radiology. 2011 ; Vol. 41, No. 7. pp. 875-883.
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