Volumetric modulated arc therapy based total body irradiation: Workflow and clinical experience with an indexed rotational immobilization system

Luo Ouyang, Michael Folkerts, You Zhang, Brian Hrycushko, Richard Lamphier, Pam Lee, Eric Chambers, Ezequiel Ramirez, Robert Reynolds, Yulong Yan, Steve B. Jiang, Robert Timmerman, Neil Desai, Ramzi Abdulrahman, Xuejun Gu

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

An indexed rotational immobilization system was developed for supine total body irradiation (TBI). Treatment plans had multi-isocentric volumetric modulated arc therapy (VMAT) beams to the upper body and parallelopposed fields to the lower body, with a 12 Gy prescription dose to > 90% of the body and mean lung dose ~8 Gy. In the end-to-end test, point dose measurements had < 10% error. Compared to conventional TBI, the VMAT-based TBI technique increased the mean dose to the body by ~1.0-1.5 Gy and decreased the mean dose to the lung by ~1.0-1.5 Gy. Overall treatment time was ~1.5 h, similar to conventional TBI.

Original languageEnglish (US)
Pages (from-to)22-25
Number of pages4
JournalPhysics and Imaging in Radiation Oncology
Volume4
DOIs
StatePublished - Oct 1 2017

Fingerprint

Intensity-Modulated Radiotherapy
Workflow
Whole-Body Irradiation
immobilization
Immobilization
therapy
arcs
irradiation
dosage
Lung
lungs
Prescriptions
Therapeutics

Keywords

  • Immobilization system
  • Total body irradiation
  • Volumetric modulated arc therapy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiation

Cite this

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title = "Volumetric modulated arc therapy based total body irradiation: Workflow and clinical experience with an indexed rotational immobilization system",
abstract = "An indexed rotational immobilization system was developed for supine total body irradiation (TBI). Treatment plans had multi-isocentric volumetric modulated arc therapy (VMAT) beams to the upper body and parallelopposed fields to the lower body, with a 12 Gy prescription dose to > 90{\%} of the body and mean lung dose ~8 Gy. In the end-to-end test, point dose measurements had < 10{\%} error. Compared to conventional TBI, the VMAT-based TBI technique increased the mean dose to the body by ~1.0-1.5 Gy and decreased the mean dose to the lung by ~1.0-1.5 Gy. Overall treatment time was ~1.5 h, similar to conventional TBI.",
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author = "Luo Ouyang and Michael Folkerts and You Zhang and Brian Hrycushko and Richard Lamphier and Pam Lee and Eric Chambers and Ezequiel Ramirez and Robert Reynolds and Yulong Yan and Jiang, {Steve B.} and Robert Timmerman and Neil Desai and Ramzi Abdulrahman and Xuejun Gu",
year = "2017",
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T1 - Volumetric modulated arc therapy based total body irradiation

T2 - Workflow and clinical experience with an indexed rotational immobilization system

AU - Ouyang, Luo

AU - Folkerts, Michael

AU - Zhang, You

AU - Hrycushko, Brian

AU - Lamphier, Richard

AU - Lee, Pam

AU - Chambers, Eric

AU - Ramirez, Ezequiel

AU - Reynolds, Robert

AU - Yan, Yulong

AU - Jiang, Steve B.

AU - Timmerman, Robert

AU - Desai, Neil

AU - Abdulrahman, Ramzi

AU - Gu, Xuejun

PY - 2017/10/1

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N2 - An indexed rotational immobilization system was developed for supine total body irradiation (TBI). Treatment plans had multi-isocentric volumetric modulated arc therapy (VMAT) beams to the upper body and parallelopposed fields to the lower body, with a 12 Gy prescription dose to > 90% of the body and mean lung dose ~8 Gy. In the end-to-end test, point dose measurements had < 10% error. Compared to conventional TBI, the VMAT-based TBI technique increased the mean dose to the body by ~1.0-1.5 Gy and decreased the mean dose to the lung by ~1.0-1.5 Gy. Overall treatment time was ~1.5 h, similar to conventional TBI.

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KW - Immobilization system

KW - Total body irradiation

KW - Volumetric modulated arc therapy

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