Vulvar lichen sclerosus in women of reproductive age

Elysha Kolitz, Laura Gammon, Melissa Mauskar

Research output: Contribution to journalArticlepeer-review

Abstract

Vulvar lichen sclerosus (vLS) is an inflammatory skin condition that predominantly affects the vulvar and perianal regions. Approximately 50% of cases present prior to menopause; however, there is a paucity of data on vLS in women of reproductive age as well as during their pregnancies. A retrospective review was performed at two tertiary referral centers to better describe cases of vLS in women of reproductive age. Thirty-three patients with a mean age of 40 years met inclusion criteria. In this group, vulvar pruritus was the most common presenting symptom (52%); 61% had biopsy-proven vLS, 42% had at least one autoimmune condition, 21% had comorbid depression or anxiety, 33% were given an incorrect diagnosis prior to vLS, and 42% had documented nonadherence to topical steroids. Among the eight patients who became pregnant, four had cesarean deliveries and 63% were symptomatic during pregnancy. When treating a woman who presents with vulvar pruritus or skin changes, vLS should be considered.

Original languageEnglish (US)
Pages (from-to)349-351
Number of pages3
JournalBaylor University Medical Center Proceedings
Volume34
Issue number3
DOIs
StatePublished - 2021

Keywords

  • Genital
  • lichen sclerosus
  • pregnancy
  • reproductive age
  • vulvar lichen sclerosuslichen sclerosus

ASJC Scopus subject areas

  • Medicine(all)

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