Waiting for the national cholesterol education program adult treatment panel IV guidelines, and in the meantime, some challenges and recommendations

Seth S. Martin, Thomas S. Metkus, Aaron Horne, Michael J. Blaha, Rani Hasan, Catherine Y. Campbell, Omair Yousuf, Parag Joshi, Sanjay Kaul, Michael Miller, Erin D. Michos, Steven R. Jones, Ty J. Gluckman, Christopher P. Cannon, Laurence S. Sperling, Roger S. Blumenthal

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The National Cholesterol Education Program Adult Treatment Panel (ATP) has provided education and guidance for decades on the management of hypercholesterolemia. Its third report (ATP III) was published 10 years ago, with a white paper update in 2004. There is a need for translation of more recent evidence into a revised guideline. To help address the significant challenges facing the ATP IV writing group, this statement aims to provide balanced recommendations that build on ATP III. The authors aim for simplicity to increase the likelihood of implementation in clinical practice. To move from ATP III to ATP IV, the authors recommend the following: (1) assess risk more accurately, (2) simplify the starting algorithm, (3) prioritize statin therapy, (4) relax the follow-up interval for repeat lipid testing, (5) designate <70 mg/dl as an "ideal" low-density lipoprotein cholesterol target, (6) endorse targets beyond low-density lipoprotein cholesterol, (7) refine therapeutic target levels to the equivalent population percentile, (8) remove misleading descriptors such as "borderline high," and (9) make lifestyle messages simpler. In conclusion, the solutions offered in this statement represent ways to translate the totality of published reports into enhanced hyperlipidemia guidelines to better combat the devastating impact of hyperlipidemia on cardiovascular health.

Original languageEnglish (US)
Pages (from-to)307-313
Number of pages7
JournalAmerican Journal of Cardiology
Volume110
Issue number2
DOIs
StatePublished - Jul 15 2012

Fingerprint

Hyperlipidemias
LDL Cholesterol
Cholesterol
Guidelines
Education
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hypercholesterolemia
Life Style
Lipids
Health
Therapeutics
Population

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Waiting for the national cholesterol education program adult treatment panel IV guidelines, and in the meantime, some challenges and recommendations. / Martin, Seth S.; Metkus, Thomas S.; Horne, Aaron; Blaha, Michael J.; Hasan, Rani; Campbell, Catherine Y.; Yousuf, Omair; Joshi, Parag; Kaul, Sanjay; Miller, Michael; Michos, Erin D.; Jones, Steven R.; Gluckman, Ty J.; Cannon, Christopher P.; Sperling, Laurence S.; Blumenthal, Roger S.

In: American Journal of Cardiology, Vol. 110, No. 2, 15.07.2012, p. 307-313.

Research output: Contribution to journalArticle

Martin, SS, Metkus, TS, Horne, A, Blaha, MJ, Hasan, R, Campbell, CY, Yousuf, O, Joshi, P, Kaul, S, Miller, M, Michos, ED, Jones, SR, Gluckman, TJ, Cannon, CP, Sperling, LS & Blumenthal, RS 2012, 'Waiting for the national cholesterol education program adult treatment panel IV guidelines, and in the meantime, some challenges and recommendations', American Journal of Cardiology, vol. 110, no. 2, pp. 307-313. https://doi.org/10.1016/j.amjcard.2012.03.023
Martin, Seth S. ; Metkus, Thomas S. ; Horne, Aaron ; Blaha, Michael J. ; Hasan, Rani ; Campbell, Catherine Y. ; Yousuf, Omair ; Joshi, Parag ; Kaul, Sanjay ; Miller, Michael ; Michos, Erin D. ; Jones, Steven R. ; Gluckman, Ty J. ; Cannon, Christopher P. ; Sperling, Laurence S. ; Blumenthal, Roger S. / Waiting for the national cholesterol education program adult treatment panel IV guidelines, and in the meantime, some challenges and recommendations. In: American Journal of Cardiology. 2012 ; Vol. 110, No. 2. pp. 307-313.
@article{35c63eabe2094476adf7f2400445cb53,
title = "Waiting for the national cholesterol education program adult treatment panel IV guidelines, and in the meantime, some challenges and recommendations",
abstract = "The National Cholesterol Education Program Adult Treatment Panel (ATP) has provided education and guidance for decades on the management of hypercholesterolemia. Its third report (ATP III) was published 10 years ago, with a white paper update in 2004. There is a need for translation of more recent evidence into a revised guideline. To help address the significant challenges facing the ATP IV writing group, this statement aims to provide balanced recommendations that build on ATP III. The authors aim for simplicity to increase the likelihood of implementation in clinical practice. To move from ATP III to ATP IV, the authors recommend the following: (1) assess risk more accurately, (2) simplify the starting algorithm, (3) prioritize statin therapy, (4) relax the follow-up interval for repeat lipid testing, (5) designate <70 mg/dl as an {"}ideal{"} low-density lipoprotein cholesterol target, (6) endorse targets beyond low-density lipoprotein cholesterol, (7) refine therapeutic target levels to the equivalent population percentile, (8) remove misleading descriptors such as {"}borderline high,{"} and (9) make lifestyle messages simpler. In conclusion, the solutions offered in this statement represent ways to translate the totality of published reports into enhanced hyperlipidemia guidelines to better combat the devastating impact of hyperlipidemia on cardiovascular health.",
author = "Martin, {Seth S.} and Metkus, {Thomas S.} and Aaron Horne and Blaha, {Michael J.} and Rani Hasan and Campbell, {Catherine Y.} and Omair Yousuf and Parag Joshi and Sanjay Kaul and Michael Miller and Michos, {Erin D.} and Jones, {Steven R.} and Gluckman, {Ty J.} and Cannon, {Christopher P.} and Sperling, {Laurence S.} and Blumenthal, {Roger S.}",
year = "2012",
month = "7",
day = "15",
doi = "10.1016/j.amjcard.2012.03.023",
language = "English (US)",
volume = "110",
pages = "307--313",
journal = "American Journal of Cardiology",
issn = "0002-9149",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Waiting for the national cholesterol education program adult treatment panel IV guidelines, and in the meantime, some challenges and recommendations

AU - Martin, Seth S.

AU - Metkus, Thomas S.

AU - Horne, Aaron

AU - Blaha, Michael J.

AU - Hasan, Rani

AU - Campbell, Catherine Y.

AU - Yousuf, Omair

AU - Joshi, Parag

AU - Kaul, Sanjay

AU - Miller, Michael

AU - Michos, Erin D.

AU - Jones, Steven R.

AU - Gluckman, Ty J.

AU - Cannon, Christopher P.

AU - Sperling, Laurence S.

AU - Blumenthal, Roger S.

PY - 2012/7/15

Y1 - 2012/7/15

N2 - The National Cholesterol Education Program Adult Treatment Panel (ATP) has provided education and guidance for decades on the management of hypercholesterolemia. Its third report (ATP III) was published 10 years ago, with a white paper update in 2004. There is a need for translation of more recent evidence into a revised guideline. To help address the significant challenges facing the ATP IV writing group, this statement aims to provide balanced recommendations that build on ATP III. The authors aim for simplicity to increase the likelihood of implementation in clinical practice. To move from ATP III to ATP IV, the authors recommend the following: (1) assess risk more accurately, (2) simplify the starting algorithm, (3) prioritize statin therapy, (4) relax the follow-up interval for repeat lipid testing, (5) designate <70 mg/dl as an "ideal" low-density lipoprotein cholesterol target, (6) endorse targets beyond low-density lipoprotein cholesterol, (7) refine therapeutic target levels to the equivalent population percentile, (8) remove misleading descriptors such as "borderline high," and (9) make lifestyle messages simpler. In conclusion, the solutions offered in this statement represent ways to translate the totality of published reports into enhanced hyperlipidemia guidelines to better combat the devastating impact of hyperlipidemia on cardiovascular health.

AB - The National Cholesterol Education Program Adult Treatment Panel (ATP) has provided education and guidance for decades on the management of hypercholesterolemia. Its third report (ATP III) was published 10 years ago, with a white paper update in 2004. There is a need for translation of more recent evidence into a revised guideline. To help address the significant challenges facing the ATP IV writing group, this statement aims to provide balanced recommendations that build on ATP III. The authors aim for simplicity to increase the likelihood of implementation in clinical practice. To move from ATP III to ATP IV, the authors recommend the following: (1) assess risk more accurately, (2) simplify the starting algorithm, (3) prioritize statin therapy, (4) relax the follow-up interval for repeat lipid testing, (5) designate <70 mg/dl as an "ideal" low-density lipoprotein cholesterol target, (6) endorse targets beyond low-density lipoprotein cholesterol, (7) refine therapeutic target levels to the equivalent population percentile, (8) remove misleading descriptors such as "borderline high," and (9) make lifestyle messages simpler. In conclusion, the solutions offered in this statement represent ways to translate the totality of published reports into enhanced hyperlipidemia guidelines to better combat the devastating impact of hyperlipidemia on cardiovascular health.

UR - http://www.scopus.com/inward/record.url?scp=84862758583&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84862758583&partnerID=8YFLogxK

U2 - 10.1016/j.amjcard.2012.03.023

DO - 10.1016/j.amjcard.2012.03.023

M3 - Article

VL - 110

SP - 307

EP - 313

JO - American Journal of Cardiology

JF - American Journal of Cardiology

SN - 0002-9149

IS - 2

ER -