TY - JOUR
T1 - Wavelength shifting of chemiluminescence using quantum dots to enhance tissue light penetration
AU - Mason, Erica A.
AU - Lopez, Ramona
AU - Mason, Ralph P.
N1 - Publisher Copyright:
© 2016 Optical Society of America.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Luminescent imaging is becoming increasingly relevant to biomedicine. Bioluminescence (BLI), and more recently, chemiluminescence (CLI) are being used to track cells in vivo and monitor specific biochemistry. However, many luminescent reactions exhibit peak emission below 550 nm, which is subject to severe tissue absorption. This study explored the ability to shift the light to longer wavelengths and demonstrated enhanced tissue penetration. Specifically, commercial Quantum Dots (800 nm) were used in conjunction with Glowsticks (model chemiluminescent reactions), and deli meats (roast turkey and beef) to mimic animal tissue.
AB - Luminescent imaging is becoming increasingly relevant to biomedicine. Bioluminescence (BLI), and more recently, chemiluminescence (CLI) are being used to track cells in vivo and monitor specific biochemistry. However, many luminescent reactions exhibit peak emission below 550 nm, which is subject to severe tissue absorption. This study explored the ability to shift the light to longer wavelengths and demonstrated enhanced tissue penetration. Specifically, commercial Quantum Dots (800 nm) were used in conjunction with Glowsticks (model chemiluminescent reactions), and deli meats (roast turkey and beef) to mimic animal tissue.
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U2 - 10.1364/OME.6.001384
DO - 10.1364/OME.6.001384
M3 - Article
AN - SCOPUS:84975230740
SN - 2159-3930
VL - 6
SP - 1384
EP - 1392
JO - Optical Materials Express
JF - Optical Materials Express
IS - 4
ER -