Wavelength shifting of chemiluminescence using quantum dots to enhance tissue light penetration

Erica A. Mason, Ramona Lopez, Ralph P. Mason

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Luminescent imaging is becoming increasingly relevant to biomedicine. Bioluminescence (BLI), and more recently, chemiluminescence (CLI) are being used to track cells in vivo and monitor specific biochemistry. However, many luminescent reactions exhibit peak emission below 550 nm, which is subject to severe tissue absorption. This study explored the ability to shift the light to longer wavelengths and demonstrated enhanced tissue penetration. Specifically, commercial Quantum Dots (800 nm) were used in conjunction with Glowsticks (model chemiluminescent reactions), and deli meats (roast turkey and beef) to mimic animal tissue.

Original languageEnglish (US)
Pages (from-to)1384-1392
Number of pages9
JournalOptical Materials Express
Volume6
Issue number4
DOIs
StatePublished - Apr 1 2016

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials

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