TY - JOUR
T1 - Web-based communications and management of a multi-center clinical trial
T2 - The Sequenced Treatment Alternatives to Relieve Depression (STAR*D) project
AU - Wisniewski, Stephen R.
AU - Eng, Heather
AU - Meloro, Leslie
AU - Gatt, Robert
AU - Ritz, Louise
AU - Stegman, Diane
AU - Trivedi, Madhukar
AU - Biggs, Melanie M.
AU - Friedman, Edward
AU - Shores-Wilson, Kathy
AU - Warden, Diane
AU - Bartolowits, Douglas
AU - Martin, Jeffrey P.
AU - Rush, A. John
PY - 2004/8
Y1 - 2004/8
N2 - While efficient methods of communication are known to be essential in conducting large multicenter clinical trials, very little information is provided on actual methods that can be implemented to improve communication. An integrated technology-based communication system was developed for the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) project, which prospectively defines treatments that are most effective for participants with a diagnosis of a nonpsychotic major depressive disorder (MDD) who report an unsatisfactory clinical outcome to an initial and, if necessary, subsequent treatment(s). This web-based communication system is comprised of a multi-faceted study Web site, including a help desk, document sharing, a project directory and reports. In addition, automated reporting via e-mail and an online data correction mechanism are also available. The STARD communication system improves communication between study personnel and improves the quality of the study's data through the integration of system elements, the integration of those elements with traditional forms of communication, by filling the gaps not addressed by those traditional methods and by reducing the staff workload burden.
AB - While efficient methods of communication are known to be essential in conducting large multicenter clinical trials, very little information is provided on actual methods that can be implemented to improve communication. An integrated technology-based communication system was developed for the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) project, which prospectively defines treatments that are most effective for participants with a diagnosis of a nonpsychotic major depressive disorder (MDD) who report an unsatisfactory clinical outcome to an initial and, if necessary, subsequent treatment(s). This web-based communication system is comprised of a multi-faceted study Web site, including a help desk, document sharing, a project directory and reports. In addition, automated reporting via e-mail and an online data correction mechanism are also available. The STARD communication system improves communication between study personnel and improves the quality of the study's data through the integration of system elements, the integration of those elements with traditional forms of communication, by filling the gaps not addressed by those traditional methods and by reducing the staff workload burden.
UR - http://www.scopus.com/inward/record.url?scp=14744286339&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=14744286339&partnerID=8YFLogxK
U2 - 10.1191/1740774504cn035oa
DO - 10.1191/1740774504cn035oa
M3 - Article
C2 - 16279277
AN - SCOPUS:14744286339
SN - 1740-7745
VL - 1
SP - 387
EP - 398
JO - Clinical Trials
JF - Clinical Trials
IS - 4
ER -