Wegener's granulomatosis presenting as lower back pain with prostatitis and ureteral obstruction

G. Middleton, D. Karp, E. Lee, J. Cush

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

A 65-year-old man presented with progressive, severe lower back pain, obstructive uropathy, and weight loss. Examination revealed a large, firm prostate, and laboratory studies included an elevated creatinine, erythrocyte sedimentation rate, and prostate specific antigen level. A chest radiograph displayed multiple nodules and a renal ultrasound demonstrated unilateral hydronephrosis. Biopsies of both the prostate and the lung showed necrotizing granulomas consistent with Wegener's granulomatosis, and the patient had positive cytoplasmic antineutrophil cytoplasmic antibodies. He was treated with cyclophosphamide with resolution of all signs and symptoms, and clearing of his radiograph. Our case represents the rare occurrence of Wegener's granulomatosis presenting as prostatitis and ureteral obstruction.

Original languageEnglish (US)
Pages (from-to)566-569
Number of pages4
JournalJournal of Rheumatology
Volume21
Issue number3
StatePublished - Jan 1 1994

Keywords

  • PROSTATE
  • PROSTATITIS
  • URETER
  • URETERAL OBSTRUCTION
  • UROLOGIC MANIFESTATIONS
  • WEGENER'S GRANULOMATOSIS

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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