Wegener's granulomatosis presenting as lower back pain with prostatitis and ureteral obstruction

G. Middleton, D. Karp, E. Lee, J. Cush

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

A 65-year-old man presented with progressive, severe lower back pain, obstructive uropathy, and weight loss. Examination revealed a large, firm prostate, and laboratory studies included an elevated creatinine, erythrocyte sedimentation rate, and prostate specific antigen level. A chest radiograph displayed multiple nodules and a renal ultrasound demonstrated unilateral hydronephrosis. Biopsies of both the prostate and the lung showed necrotizing granulomas consistent with Wegener's granulomatosis, and the patient had positive cytoplasmic antineutrophil cytoplasmic antibodies. He was treated with cyclophosphamide with resolution of all signs and symptoms, and clearing of his radiograph. Our case represents the rare occurrence of Wegener's granulomatosis presenting as prostatitis and ureteral obstruction.

Original languageEnglish (US)
Pages (from-to)566-569
Number of pages4
JournalJournal of Rheumatology
Volume21
Issue number3
StatePublished - 1994

Fingerprint

Ureteral Obstruction
Prostatitis
Granulomatosis with Polyangiitis
Low Back Pain
Prostate
Antineutrophil Cytoplasmic Antibodies
Hydronephrosis
Blood Sedimentation
Prostate-Specific Antigen
Granuloma
Cyclophosphamide
Signs and Symptoms
Weight Loss
Creatinine
Thorax
Kidney
Biopsy
Lung

Keywords

  • PROSTATE
  • PROSTATITIS
  • URETER
  • URETERAL OBSTRUCTION
  • UROLOGIC MANIFESTATIONS
  • WEGENER'S GRANULOMATOSIS

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

Wegener's granulomatosis presenting as lower back pain with prostatitis and ureteral obstruction. / Middleton, G.; Karp, D.; Lee, E.; Cush, J.

In: Journal of Rheumatology, Vol. 21, No. 3, 1994, p. 566-569.

Research output: Contribution to journalArticle

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