Welcoming Foxa2 in the Bile Acid Entourage

Antonio Moschetta

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations

Abstract

Homeostatic regulation of bile acid metabolism and biliary lipid secretion is critical to prevent enterohepatic diseases. Kaestner and coworkers (Bochkis et al., 2008) show that loss of forkhead box transcription factor Foxa2 in the liver leads to hepatic injury due to downregulation in the expression levels of bile acid transporters and detoxification enzymes.

Original languageEnglish (US)
Pages (from-to)276-278
Number of pages3
JournalCell Metabolism
Volume8
Issue number4
DOIs
StatePublished - Oct 8 2008

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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