When does metoclopramide facilitate transpyloric intubation?

K. Whatley, W. W. Turner, M. Dey, J. Leonard, M. Guthrie

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Postpyloric feeding probably reduces the incidence of tracheobronchial aspiration and improves feeding tolerance. However, duodenal intubation is often unsuccessful in critically ill patients due to gastric atony. Metoclopramide improves gastric emptying. In a pilot study, 12 adult patients were administered 10 to 20 mg of intravenous metoclopramide after weighted nasal feeding tubes had failed to spontaneously pass distal to the pylorus. In no patient did metoclopramide induce transpyloric passage of the tube. A randomized prospective study involving 10 adult patients was conducted to examine the effect of preinsertion intravenous metoclopramide on transpyloric intubation. All patients had failed to achieve spontaneous duodenal intubation. Five patients received 20 mg of metoclopramide 10 min prior to nasal insertion of a weighed feeding tube. Five control patients received no premedication. Four metoclopramide patients achieved duodenal intubation immediately. In none of the control patients did transpyloric intubation occur (p=0.048). Metoclopramide, administered after nasogastric intubation, is ineffective in promoting transpyloric advancement of feeding tubes. There is a significant increase in transpyloric intubation when metoclopramide is administered prior to tube insertion.

Original languageEnglish (US)
Pages (from-to)679-681
Number of pages3
JournalJournal of Parenteral and Enteral Nutrition
Volume8
Issue number6
StatePublished - 1984

Fingerprint

metoclopramide
Metoclopramide
Intubation
tube feeding
Enteral Nutrition
Nose
Gastrointestinal Intubation
pylorus
gastric emptying
Premedication
Gastric Emptying
Pylorus
enteral feeding
prospective studies
Critical Illness
Stomach
stomach
Prospective Studies
incidence

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

When does metoclopramide facilitate transpyloric intubation? / Whatley, K.; Turner, W. W.; Dey, M.; Leonard, J.; Guthrie, M.

In: Journal of Parenteral and Enteral Nutrition, Vol. 8, No. 6, 1984, p. 679-681.

Research output: Contribution to journalArticle

Whatley, K, Turner, WW, Dey, M, Leonard, J & Guthrie, M 1984, 'When does metoclopramide facilitate transpyloric intubation?', Journal of Parenteral and Enteral Nutrition, vol. 8, no. 6, pp. 679-681.
Whatley, K. ; Turner, W. W. ; Dey, M. ; Leonard, J. ; Guthrie, M. / When does metoclopramide facilitate transpyloric intubation?. In: Journal of Parenteral and Enteral Nutrition. 1984 ; Vol. 8, No. 6. pp. 679-681.
@article{345b2a90a55e4861b808bd4de1fadb2f,
title = "When does metoclopramide facilitate transpyloric intubation?",
abstract = "Postpyloric feeding probably reduces the incidence of tracheobronchial aspiration and improves feeding tolerance. However, duodenal intubation is often unsuccessful in critically ill patients due to gastric atony. Metoclopramide improves gastric emptying. In a pilot study, 12 adult patients were administered 10 to 20 mg of intravenous metoclopramide after weighted nasal feeding tubes had failed to spontaneously pass distal to the pylorus. In no patient did metoclopramide induce transpyloric passage of the tube. A randomized prospective study involving 10 adult patients was conducted to examine the effect of preinsertion intravenous metoclopramide on transpyloric intubation. All patients had failed to achieve spontaneous duodenal intubation. Five patients received 20 mg of metoclopramide 10 min prior to nasal insertion of a weighed feeding tube. Five control patients received no premedication. Four metoclopramide patients achieved duodenal intubation immediately. In none of the control patients did transpyloric intubation occur (p=0.048). Metoclopramide, administered after nasogastric intubation, is ineffective in promoting transpyloric advancement of feeding tubes. There is a significant increase in transpyloric intubation when metoclopramide is administered prior to tube insertion.",
author = "K. Whatley and Turner, {W. W.} and M. Dey and J. Leonard and M. Guthrie",
year = "1984",
language = "English (US)",
volume = "8",
pages = "679--681",
journal = "Journal of Parenteral and Enteral Nutrition",
issn = "0148-6071",
publisher = "SAGE Publications Inc.",
number = "6",

}

TY - JOUR

T1 - When does metoclopramide facilitate transpyloric intubation?

AU - Whatley, K.

AU - Turner, W. W.

AU - Dey, M.

AU - Leonard, J.

AU - Guthrie, M.

PY - 1984

Y1 - 1984

N2 - Postpyloric feeding probably reduces the incidence of tracheobronchial aspiration and improves feeding tolerance. However, duodenal intubation is often unsuccessful in critically ill patients due to gastric atony. Metoclopramide improves gastric emptying. In a pilot study, 12 adult patients were administered 10 to 20 mg of intravenous metoclopramide after weighted nasal feeding tubes had failed to spontaneously pass distal to the pylorus. In no patient did metoclopramide induce transpyloric passage of the tube. A randomized prospective study involving 10 adult patients was conducted to examine the effect of preinsertion intravenous metoclopramide on transpyloric intubation. All patients had failed to achieve spontaneous duodenal intubation. Five patients received 20 mg of metoclopramide 10 min prior to nasal insertion of a weighed feeding tube. Five control patients received no premedication. Four metoclopramide patients achieved duodenal intubation immediately. In none of the control patients did transpyloric intubation occur (p=0.048). Metoclopramide, administered after nasogastric intubation, is ineffective in promoting transpyloric advancement of feeding tubes. There is a significant increase in transpyloric intubation when metoclopramide is administered prior to tube insertion.

AB - Postpyloric feeding probably reduces the incidence of tracheobronchial aspiration and improves feeding tolerance. However, duodenal intubation is often unsuccessful in critically ill patients due to gastric atony. Metoclopramide improves gastric emptying. In a pilot study, 12 adult patients were administered 10 to 20 mg of intravenous metoclopramide after weighted nasal feeding tubes had failed to spontaneously pass distal to the pylorus. In no patient did metoclopramide induce transpyloric passage of the tube. A randomized prospective study involving 10 adult patients was conducted to examine the effect of preinsertion intravenous metoclopramide on transpyloric intubation. All patients had failed to achieve spontaneous duodenal intubation. Five patients received 20 mg of metoclopramide 10 min prior to nasal insertion of a weighed feeding tube. Five control patients received no premedication. Four metoclopramide patients achieved duodenal intubation immediately. In none of the control patients did transpyloric intubation occur (p=0.048). Metoclopramide, administered after nasogastric intubation, is ineffective in promoting transpyloric advancement of feeding tubes. There is a significant increase in transpyloric intubation when metoclopramide is administered prior to tube insertion.

UR - http://www.scopus.com/inward/record.url?scp=0021679850&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021679850&partnerID=8YFLogxK

M3 - Article

C2 - 6441010

AN - SCOPUS:0021679850

VL - 8

SP - 679

EP - 681

JO - Journal of Parenteral and Enteral Nutrition

JF - Journal of Parenteral and Enteral Nutrition

SN - 0148-6071

IS - 6

ER -