White Matter Changes and Confrontation Naming in Retired Aging National Football League Athletes

Jeremy F. Strain, Nyaz Didehbani, Jeffrey Spence, Heather Conover, Elizabeth K. Bartz, Sethesh Mansinghani, Myrtle K. Jeroudi, Neena K. Rao, Lindy M. Fields, Michael A. Kraut, C. Munro Cullum, John Hart, Kyle B. Womack

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Using diffusion tensor imaging (DTI), we assessed the relationship of white matter integrity and performance on the Boston Naming Test (BNT) in a group of retired professional football players and a control group. We examined correlations between fractional anisotropy (FA) and mean diffusivity (MD) with BNT T-scores in an unbiased voxelwise analysis processed with tract-based spatial statistics (TBSS). We also analyzed the DTI data by grouping voxels together as white matter tracts and testing each tract's association with BNT T-scores. Significant voxelwise correlations between FA and BNT performance were only seen in the retired football players (p < 0.02). Two tracts had mean FA values that significantly correlated with BNT performance: forceps minor and forceps major. White matter integrity is important for distributed cognitive processes, and disruption correlates with diminished performance in athletes exposed to concussive and subconcussive brain injuries, but not in controls without such exposure.

Original languageEnglish (US)
Pages (from-to)372-379
Number of pages8
JournalJournal of Neurotrauma
Volume34
Issue number2
DOIs
StatePublished - Jan 15 2017

Fingerprint

Football
Athletes
Anisotropy
Diffusion Tensor Imaging
Surgical Instruments
Brain Injuries
White Matter
Control Groups

Keywords

  • concussion
  • DTI
  • naming
  • National Football League
  • TBSS
  • white matter

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

White Matter Changes and Confrontation Naming in Retired Aging National Football League Athletes. / Strain, Jeremy F.; Didehbani, Nyaz; Spence, Jeffrey; Conover, Heather; Bartz, Elizabeth K.; Mansinghani, Sethesh; Jeroudi, Myrtle K.; Rao, Neena K.; Fields, Lindy M.; Kraut, Michael A.; Cullum, C. Munro; Hart, John; Womack, Kyle B.

In: Journal of Neurotrauma, Vol. 34, No. 2, 15.01.2017, p. 372-379.

Research output: Contribution to journalArticle

Strain, JF, Didehbani, N, Spence, J, Conover, H, Bartz, EK, Mansinghani, S, Jeroudi, MK, Rao, NK, Fields, LM, Kraut, MA, Cullum, CM, Hart, J & Womack, KB 2017, 'White Matter Changes and Confrontation Naming in Retired Aging National Football League Athletes', Journal of Neurotrauma, vol. 34, no. 2, pp. 372-379. https://doi.org/10.1089/neu.2016.4446
Strain, Jeremy F. ; Didehbani, Nyaz ; Spence, Jeffrey ; Conover, Heather ; Bartz, Elizabeth K. ; Mansinghani, Sethesh ; Jeroudi, Myrtle K. ; Rao, Neena K. ; Fields, Lindy M. ; Kraut, Michael A. ; Cullum, C. Munro ; Hart, John ; Womack, Kyle B. / White Matter Changes and Confrontation Naming in Retired Aging National Football League Athletes. In: Journal of Neurotrauma. 2017 ; Vol. 34, No. 2. pp. 372-379.
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