White matter tract integrity predicts visual search performance in young and older adults

Ilana J. Bennett, Michael A. Motes, Neena K. Rao, Bart Rypma

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Functional imaging research has identified frontoparietal attention networks involved in visual search, with mixed evidence regarding whether different networks are engaged when the search target differs from distracters by a single (elementary) versus multiple (conjunction) features. Neural correlates of visual search, and their potential dissociation, were examined here using integrity of white matter connecting the frontoparietal networks. The effect of aging on these brain-behavior relationships was also of interest. Younger and older adults performed a visual search task and underwent diffusion tensor imaging (DTI) to reconstruct 2 frontoparietal (superior and inferior longitudinal fasciculus; SLF and ILF) and 2 midline (genu, splenium) white matter tracts. As expected, results revealed age-related declines in conjunction, but not elementary, search performance; and in ILF and genu tract integrity. Importantly, integrity of the superior longitudinal fasciculus, ILF, and genu tracts predicted search performance (conjunction and elementary), with no significant age group differences in these relationships. Thus, integrity of white matter tracts connecting frontoparietal attention networks contributes to search performance in younger and older adults.

Original languageEnglish (US)
JournalNeurobiology of Aging
Volume33
Issue number2
DOIs
StatePublished - Feb 2012

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Young Adult
Diffusion Tensor Imaging
Age Groups
Brain
Research
White Matter

Keywords

  • Aging
  • Diffusion tensor imaging
  • Visual search
  • White matter integrity

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)
  • Aging
  • Developmental Biology
  • Geriatrics and Gerontology

Cite this

White matter tract integrity predicts visual search performance in young and older adults. / Bennett, Ilana J.; Motes, Michael A.; Rao, Neena K.; Rypma, Bart.

In: Neurobiology of Aging, Vol. 33, No. 2, 02.2012.

Research output: Contribution to journalArticle

Bennett, Ilana J. ; Motes, Michael A. ; Rao, Neena K. ; Rypma, Bart. / White matter tract integrity predicts visual search performance in young and older adults. In: Neurobiology of Aging. 2012 ; Vol. 33, No. 2.
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