Why Can't We Just Use PCR? The Role of Genotypic versus Phenotypic Testing for Antimicrobial Resistance Testing

Jennifer Dien Bard, Francesca Lee

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

There is a need for phenotypic susceptibility testing that is expeditious and that can be performed directly from clinical specimens. While rapid pathogen identification is important, it is the susceptibility result that is essential for antimicrobial optimization. The options for rapid susceptibility testing are limited, with the majority of commercial tests available offering genotypic resistance detection only. In this article, a laboratorian and a clinician discuss the benefits and limitations of genotypic and phenotypic susceptibility testing and provide examples of how results should be interpreted to maximize the clinical utility.

Original languageEnglish (US)
Pages (from-to)87-95
Number of pages9
JournalClinical Microbiology Newsletter
Volume40
Issue number11
DOIs
StatePublished - Jun 1 2018

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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