Yb‐DTPA, a novel contrast agent in magnetic resonance imaging: Application to rat kidney

S. K. Sarkar, R. E. Rycyna, R. E. Lenkinski, H. A. Solleveld, L. B. Kinter

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

We have developed a novel contrast agent, ytterbium‐diethylenetriamine pentaacetic acid (Yb‐DTPA), for magnetic resonance imaging (MRI) and its mechanism of action is predominantly by the susceptibility mechanism. We have applied this contrast agent for renal MRI studies. We also demonstrate that Yb‐DTPA has a renal clearance similar to that of inulin in rats and may therefore be useful for the estimation of glomerular filtration rate. © 1991 Academic Press, Inc.

Original languageEnglish (US)
Pages (from-to)328-335
Number of pages8
JournalMagnetic resonance in medicine
Volume17
Issue number2
DOIs
StatePublished - Feb 1991

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Sarkar, S. K., Rycyna, R. E., Lenkinski, R. E., Solleveld, H. A., & Kinter, L. B. (1991). Yb‐DTPA, a novel contrast agent in magnetic resonance imaging: Application to rat kidney. Magnetic resonance in medicine, 17(2), 328-335. https://doi.org/10.1002/mrm.1910170205