Zinc deficiency: An unexpected trigger for autophagy

Binbin Ding, Qing Zhong

Research output: Contribution to journalReview article

9 Scopus citations

Abstract

Cells respond to deprivation of certain nutrients such as glucose or nitrogen by inducing autophagy, reclaiming pieces of proteins for use in critical functions. A recent study shows that, in yeast, zinc depletion acts in a similar fashion. Depletion of this essential nutrient induces non-selective autophagy by inhibiting TORC1, leading to release and recycling of zinc from degraded proteins.

Original languageEnglish (US)
Pages (from-to)8531-8532
Number of pages2
JournalJournal of Biological Chemistry
Volume292
Issue number20
DOIs
StatePublished - May 19 2017

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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