Abstract
Purpose: To demonstrate the utility of a "reduced field-of-view" (zoom imaging) technique to accelerate free-breathing, ECG-triggered, turbo-spin-echo black-blood sequences, which have been previously described to detect subclinical aortic atherosclerosis. Materials and Methods: Fifteen healthy volunteers underwent MRI of the thoracic and abdominal aorta. Imaging with the conventional full field-of-view sequence was compared with zoom imaging. Total scan time, image quality (i.e., contrast-to-noise ratio and vessel wall sharpness) and vessel wall thickness were analyzed. A subgroup of 10 volunteers also underwent acceleration of imaging using sensitivity encoding (SENSE) for comparison. Results: Zoom imaging significantly reduced imaging time from a mean of 41 ± 9 min (conventional imaging) to 15 ± 0.5 min (P < 0.01). There was no difference in image quality between conventional and zoom imaging with respect to CNR (10.1 ± 6 versus 10.1 ± 6) or vessel wall sharpness (38 ± 4% versus 39 ± 4%). Furthermore, Bland Altman plots showed excellent agreement in vessel wall thickness measurements using the two methods. In comparison, SENSE not only reduced CNR but also resulted in underestimation of vessel wall thickness compared with the conventional sequence. Conclusion: Zoom imaging allows accurate and time-efficient imaging of the abdominal and thoracic aorta for cardiovascular risk prediction. In this application, it is preferable to SENSE.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 279-285 |
| Number of pages | 7 |
| Journal | Journal of Magnetic Resonance Imaging |
| Volume | 34 |
| Issue number | 2 |
| DOIs | |
| State | Published - Aug 1 2011 |
Fingerprint
Keywords
- aorta
- atherosclerosis
- cardiovascular system
- magnetic resonance imaging
- risk factors
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Zoom imaging for rapid aortic vessel wall imaging and cardiovascular risk assessment. / Hussain, Tarique; Clough, Rachel E.; Cecelja, Marina; Makowski, Marcus; Peel, Sarah; Chowienczyk, Philip; Schaeffter, Tobias; Greil, Gerald; Botnar, Rene.
In: Journal of Magnetic Resonance Imaging, Vol. 34, No. 2, 01.08.2011, p. 279-285.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Zoom imaging for rapid aortic vessel wall imaging and cardiovascular risk assessment
AU - Hussain, Tarique
AU - Clough, Rachel E.
AU - Cecelja, Marina
AU - Makowski, Marcus
AU - Peel, Sarah
AU - Chowienczyk, Philip
AU - Schaeffter, Tobias
AU - Greil, Gerald
AU - Botnar, Rene
PY - 2011/8/1
Y1 - 2011/8/1
N2 - Purpose: To demonstrate the utility of a "reduced field-of-view" (zoom imaging) technique to accelerate free-breathing, ECG-triggered, turbo-spin-echo black-blood sequences, which have been previously described to detect subclinical aortic atherosclerosis. Materials and Methods: Fifteen healthy volunteers underwent MRI of the thoracic and abdominal aorta. Imaging with the conventional full field-of-view sequence was compared with zoom imaging. Total scan time, image quality (i.e., contrast-to-noise ratio and vessel wall sharpness) and vessel wall thickness were analyzed. A subgroup of 10 volunteers also underwent acceleration of imaging using sensitivity encoding (SENSE) for comparison. Results: Zoom imaging significantly reduced imaging time from a mean of 41 ± 9 min (conventional imaging) to 15 ± 0.5 min (P < 0.01). There was no difference in image quality between conventional and zoom imaging with respect to CNR (10.1 ± 6 versus 10.1 ± 6) or vessel wall sharpness (38 ± 4% versus 39 ± 4%). Furthermore, Bland Altman plots showed excellent agreement in vessel wall thickness measurements using the two methods. In comparison, SENSE not only reduced CNR but also resulted in underestimation of vessel wall thickness compared with the conventional sequence. Conclusion: Zoom imaging allows accurate and time-efficient imaging of the abdominal and thoracic aorta for cardiovascular risk prediction. In this application, it is preferable to SENSE.
AB - Purpose: To demonstrate the utility of a "reduced field-of-view" (zoom imaging) technique to accelerate free-breathing, ECG-triggered, turbo-spin-echo black-blood sequences, which have been previously described to detect subclinical aortic atherosclerosis. Materials and Methods: Fifteen healthy volunteers underwent MRI of the thoracic and abdominal aorta. Imaging with the conventional full field-of-view sequence was compared with zoom imaging. Total scan time, image quality (i.e., contrast-to-noise ratio and vessel wall sharpness) and vessel wall thickness were analyzed. A subgroup of 10 volunteers also underwent acceleration of imaging using sensitivity encoding (SENSE) for comparison. Results: Zoom imaging significantly reduced imaging time from a mean of 41 ± 9 min (conventional imaging) to 15 ± 0.5 min (P < 0.01). There was no difference in image quality between conventional and zoom imaging with respect to CNR (10.1 ± 6 versus 10.1 ± 6) or vessel wall sharpness (38 ± 4% versus 39 ± 4%). Furthermore, Bland Altman plots showed excellent agreement in vessel wall thickness measurements using the two methods. In comparison, SENSE not only reduced CNR but also resulted in underestimation of vessel wall thickness compared with the conventional sequence. Conclusion: Zoom imaging allows accurate and time-efficient imaging of the abdominal and thoracic aorta for cardiovascular risk prediction. In this application, it is preferable to SENSE.
KW - aorta
KW - atherosclerosis
KW - cardiovascular system
KW - magnetic resonance imaging
KW - risk factors
UR - http://www.scopus.com/inward/record.url?scp=79960612652&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79960612652&partnerID=8YFLogxK
U2 - 10.1002/jmri.22617
DO - 10.1002/jmri.22617
M3 - Article
C2 - 21780223
AN - SCOPUS:79960612652
VL - 34
SP - 279
EP - 285
JO - Journal of Magnetic Resonance Imaging
JF - Journal of Magnetic Resonance Imaging
SN - 1053-1807
IS - 2
ER -